27 citations
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April 2011 in “Folia Histochemica et Cytobiologica” DHT deficiency can disrupt cell connections in rat testes, possibly affecting fertility.
Blocking 5α-reductase can reduce sleep deprivation-related behavioral issues in rats.
8 citations
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June 2020 in “Dermatologic Therapy” Hair loss lowers quality of life, causing embarrassment, frustration, and sexual rejection.
January 2023 in “Skin appendage disorders” Low-dose oral minoxidil may help treat hair loss but is not FDA-approved and can cause side effects like unwanted hair growth and heart issues.
1 citations
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January 1997 in “ACP journal club”
January 2020 in “The Journal of Sexual Medicine” Using 5α-reductase inhibitors for hair loss can cause lasting sexual, physical, mental, and vascular health issues in men, even after stopping the medication.
April 2016 in “The Journal of Sexual Medicine” PFS affects some women, steroids easily bought online, hypogonadism info unreliable, low testosterone linked to CVD.
April 2017 in “The Journal of urology/The journal of urology” Long-term use of certain prostate drugs can worsen erectile dysfunction by changing penile tissue, especially in rats with high blood pressure.
December 2016 in “The journal of sexual medicine” Many patients with lower urinary tract symptoms also have undiagnosed erectile dysfunction, which improves with treatment.
40 citations
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January 1973 in “Journal of Dairy Science” Zinc deficiency in male goats leads to poor hair growth, smaller testicles, reduced libido, and is hard to reverse.
October 2023 in “Georgetown medical review” Finasteride and Dutasteride can improve hair growth in male baldness but may cause temporary sexual dysfunction and possibly affect fertility.
49 citations
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December 2007 in “Fertility and Sterility” Stopping finasteride improved sperm counts in two men, reducing the need for fertility treatments.
Propecia users with Androgenic Alopecia experienced a lower quality of life and more serious side effects compared to those using Minoxidil.
May 2021 in “Journal of the Endocrine Society” A woman's hair loss and other symptoms were due to a rare hormone deficiency treatable with steroids.
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January 2009 in “PubMed” Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.
34 citations
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January 2004 in “PubMed” DHT deficiency in rats reduces sperm content and affects testis structure over time.
May 2023 in “The journal of sexual medicine” Ovarian Hyperthecosis caused hypersexuality in an older woman and was successfully treated with surgery.
54 citations
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September 2013 in “Fertility and Sterility” Finasteride can reduce fertility in some men, but stopping it increases sperm count.
October 2017 in “The Journal of Urology” Finasteride reduces the need for prostate surgery but may increase the risk of depression and persistent sexual side effects.
24 citations
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March 2017 in “Journal of The European Academy of Dermatology and Venereology” Finasteride use linked to increased risk of sexual dysfunction, especially in younger people.
April 2024 in “JCEM case reports” A man's breast enlargement from low-dose finasteride for hair loss didn't go away, even with treatment, and might be more common than reported.
12 citations
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January 2020 in “Skin appendage disorders” Low-dose oral minoxidil effectively treats female hair loss with good safety.
7 citations
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April 2021 in “Journal of Clinical Psychopharmacology” Finasteride may increase the risk of depression, anxiety, and suicidal thoughts.
September 2025 in “Therapies” Finasteride use for hair loss may cause depression and suicidal thoughts, requiring careful monitoring.
1 citations
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December 2016 in “The Journal of Sexual Medicine” Many different biological, psychological, and social factors can cause sexual dysfunction in American women.
August 2009 in “Reactions Weekly” Finasteride caused breast enlargement in two men, which improved after stopping the medication.
28 citations
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July 2022 in “Endocrine” Low prolactin in young women may increase heart and metabolism risks.
January 2026 in “Dermatology Practical & Conceptual” Diffuse lichen planopilaris greatly reduces quality of life.
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September 2014 in “JAMA Dermatology” 46 citations
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November 2014 in “The Journal of Clinical Endocrinology & Metabolism” Men with isolated hypogonadotropic hypogonadism have partial steroid deficiencies, while those with panhypopituitarism have severe deficiencies.