research Correlation of toxicity with pharmacokinetics of pegylated liposomal doxorubicin (Doxil) in metastatic breast carcinoma
Doxil's toxicity varies with dose and schedule, and pharmacokinetic guidance can optimize dosing.
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150-180 / 1000+ resultsresearch Pediatric Endocrine-Disrupting Chemical Exposure Produces Irreversible Organizational Injury: Biomarker Evidence Necessitating a Precautionary Public Health Framework
Endocrine-disrupting chemicals cause irreversible harm to children's development, increasing disease risk.
research Adverse Effects of the 5-Alpha-Reductase Inhibitor Finasteride on Daphnia Magna: Endocrine System and Lipid Metabolism Disruption
Finasteride harms Daphnia magna's reproduction and metabolism.
research Anagen effluvium due to thallium poisoning derived from the intake of Chinese herbal medicine and rodenticide containing thallium salts
A woman and her daughter had thallium poisoning from a herbal drink and rodenticide, causing hair loss and other symptoms.
research Unsaturated Halogenated Hydrocarbons
These chemicals can be toxic, causing health issues like cancer, liver damage, and irritation.
research Small Mammal Populations and Community under Conditions of Extremely High Thallium Contamination in the Environment
High thallium contamination severely harms small mammal populations, causing health issues and low population density.
research K6/ODC transgenic mice as a sensitive model for carcinogen identification
K6/ODC transgenic mice are effective for quickly identifying cancer-causing chemicals.
research Epidermal cell proliferation and modulation of the protective potency of dexamethasone against phorbol ester-induced ornithine decarboxylase activity
Dexamethasone reduces inflammation and delays skin cell changes caused by TPA.
research Tea Polyphenol–Zinc Nanocomplexes Alleviate Diquat-Induced Liver and Small Intestine Oxidative Stress in C57BL/6 Mice
Tea polyphenol–zinc helps protect the liver and intestines from oxidative stress.
research Outbreak of thallium poisoning among Iraqi patients
Thallium poisoning from contaminated cake caused severe health issues in Baghdad, highlighting the need to ban thallium as a rodenticide.
research N-methylformamide induces multiple organ toxicity in Fischer 344 rats
research Unsaturated Halogenated Hydrocarbons
These chemicals can be toxic and cause health issues like irritation, liver damage, and cancer.
research Diphenyl cresyl phosphate [MAK Value Documentations, 2003]
Diphenyl cresyl phosphate has low toxicity but can harm the liver, kidneys, adrenal glands, and testicles at high doses.
research Mechanistic Approach on the Pulmonary Oxido-Inflammatory Stress Induced by Cobalt Ferrite Nanoparticles in Rats
Daily intake of 0.5 or 5 mg cobalt ferrite nanoparticles can harm lungs through oxidative and inflammatory stress.
research Thallium
Thallium exposure can cause serious health issues, including nerve damage and hair loss.
research Zone 1 Hepatocellular Necrosis: A Manifestation of Selenium Toxicity?
Excessive selenium intake can cause liver damage.
research Delta‐6 desaturase knockout mouse illustrates previously undocumented pathology
Lack of certain fatty acids causes skin, immune, and fertility issues in mice.
research Thallium - poisoner’s poison: An overview and review of current knowledge on the toxicological effects and mechanisms
Thallium is highly toxic, causing severe health issues, and Prussian blue is the best antidote.
research Hepato- and neuro-toxicity by ethylenthiourea.
Ethylenthiourea is toxic to the liver and nervous system, especially with alcohol.
research Acquired Generalized Hypertrichosis Due to Diazoxide
A 6-year-old boy developed excessive hair growth after taking diazoxide for low blood sugar.
research Biochemical and histological effects of feeding thermally oxidized rapeseed oil and lard to rats.
Feeding rats oxidized rapeseed oil and lard caused weight loss, organ damage, and toxicity symptoms.
research Long-term toxicologic and tumorigenesis studies on an oral contraceptive agent in albino rats
research Experimental Production of Cutaneous Calcinosis and Sclerosis with Dihydrotachysterol (AT-10) 1
Giving dihydrotachysterol to mother rats caused skin hardening and bone issues in their babies through milk.
research Evaluation of Potential Toxicity of Calotropis gigantea Leaf Extract on Danio rerio: Bioactive Compounds, Oxidative Stress and Histological Toxicity Analysis
Calotropis gigantea leaf extract causes significant tissue damage and stress in fish.
research Chronische Thalliumintoxikation: Beobachtung einer kriminellen Vergiftung
A man was poisoned with thallium, treated successfully, but still had some nerve issues after 6 months.
research Case of thallium intoxication
This document presents a case of thallium intoxication in a 38-year-old woman who exhibited symptoms such as subacute sensory-motor polyneuropathy, hepatitis, and alopecia. Thallium compounds are highly toxic, affecting glucose metabolism and causing neurological and dermatological symptoms. The patient showed elevated liver enzymes and low potassium levels, with tests confirming high thallium levels in her serum and urine. Treatment with potassium hexacyanoferrate, an antidote, led to a positive outcome, with full resolution of symptoms and hair regrowth after one year. Thallium intoxication is rare and challenging to diagnose, requiring differentiation from other heavy metal intoxications and autoimmune diseases. Prompt administration of the antidote is crucial for effective treatment.
research Thallium in rodenticide- banned or not..!!!- Two case reports
Thallium poisoning is dangerous but treatable with specific medical interventions.
research Adverse Systemic Reaction to Dinitrochlorobenzene
A man had bad reactions to a hair loss treatment called DNCB.
research Diagnosis and treatment of polonium poisoning
Polonium poisoning is diagnosed by detecting it in urine and feces, and treated with supportive care, infection prevention, and chelation therapy.
research A Definitive Role of Ornithine Decarboxylase in Photocarcinogenesis
Inhibiting ODC can prevent UV-induced skin cancer.