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research Keratinocytes maintain compartmentalization between dermal papilla and fibroblasts in 3D heterotypic tri‐cultures

16 citations , August 2019 in “Cell Proliferation”

Keratinocytes help keep hair follicle cells and skin cells separate in 3D cultures, which is important for hair growth research.

research The CD44+ALDH+ Population of Human Keratinocytes Is Enriched for Epidermal Stem Cells with Long-Term Repopulating Ability

28 citations , January 2013 in “Stem cells”

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

research Concerted gene duplications in the two keratin gene families

53 citations , May 1988 in “Journal of Molecular Evolution”

research Coexpression of Keratins Characteristic of Skin and Hair Differentiation in Nail Cells

23 citations , February 1993 in “Journal of Investigative Dermatology”

research A new look into an old problem: keratins as tools to investigate determination, morphogenesis, and differentiation in skin.

156 citations , January 1989 in “Genes & Development”

Keratin expression reflects cell organization and differentiation, not causes it.

research Two- and Three-Dimensional Culture of Keratinocyte Stem and Precursor Cells Derived from Primary Murine Epidermal Cultures

28 citations , September 2011 in “Stem Cell Reviews and Reports”

research [Difference between the hair follicle cell and epidermal keratinocyte in vitro].

February 1990 in “PubMed”

Hair follicle cells and skin cells differ in keratinization and other features.

research Three cDNA sequences of mouse type I keratins. Cellular localization of the mRNAs in normal and hyperproliferative tissues.

57 citations , January 1987 in “Journal of Biological Chemistry”

Different keratins have unique expression patterns in mouse skin cells.

research Dermal papilla cells induce keratinocyte tubulogenesis in culture

28 citations , March 2010 in “Histochemistry and cell biology”

Skin cells can help create early hair-like structures in lab cultures.

Induced Pluripotent Stem Cell Derived Keratinocyte Differentiation from Reprogrammed Blood Cells

research 858 IPSC derived keratinocyte differentiation from reprogrammed blood cells

April 2017 in “Journal of Investigative Dermatology”

Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.

research Human hair follicle cells of outer root sheath maintain their genuine keratin expression in vitro

1 citations , June 1986

research Cell Density-Dependent Upregulation of PDCD4 in Keratinocytes and Its Implications for Epidermal Homeostasis and Repair

10 citations , December 2015 in “International Journal of Molecular Sciences”

PDCD4 is important for controlling skin cell growth and healing.

research In-vivo dedifferentiation of keratinocytes to epidermal stem cells

1 citations , February 2002 in “The Lancet”

Keratinocytes might turn into stem cells, but more research is needed to confirm this.

research Differentiation of Mouse Induced Pluripotent Stem Cells into a Multipotent Keratinocyte Lineage

101 citations , December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology”

Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.

research Keratin expression in the human hair follicle

1 citations , January 1989 in “Springer eBooks”

research Keratinocytes regulate the function of melanocytes

55 citations , December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì”

Keratinocytes control how melanocytes work.

Manipulation of Stem Cell Divisional Behavior: Selectively Promoting Asymmetric and Symmetric Keratinocyte Divisions In Vitro

research 876 Manipulation of stem cell divisional behavior: Selectively promoting asymmetric and symmetric keratinocyte divisions in vitro

April 2017 in “Journal of Investigative Dermatology”

Scientists can control how skin stem cells divide by using different treatments.

research Deriving Keratinocyte Progenitor Cells and Keratinocytes from Human‐Induced Pluripotent Stem Cells

10 citations , August 2020 in “Current protocols in stem cell biology”

Scientists developed a way to create skin and hair cells from human stem cells, which could help treat burns and restore hair.

research Revisiting the significance of keratin expression in complex epithelia

6 citations , October 2022 in “Journal of cell science”

Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.

research Keratins 1 and 10 or homologues as regular constituents of inner root sheath and cuticle cells in the human hair follicle.

44 citations , August 1990 in “PubMed”

Keratins K1 and K10 are found in the inner root sheath and cuticle of human hair follicles.

research Expression of keratin K14 in the epidermis and hair follicle: insights into complex programs of differentiation.

198 citations , November 1989 in “The Journal of Cell Biology”

Keratin K14 expression varies between hair follicles and epidermis, affecting cell differentiation.

research Keratinocyte stem cells of cornea, skin and hair follicles

28 citations , January 1997 in “Elsevier eBooks”

Keratinocyte stem cells help regenerate and repair cornea, skin, and hair.

research Keratin expression in basal cell carcinomas

128 citations , February 1992 in “British Journal of Dermatology”

Basal cell carcinomas likely originate from hair follicle cells or stem cells.

research Dermal papilla cells induce keratinocyte tubulogenesis in culture Elina S. ChermnykhEkaterina A. VorotelyakKsenia Y. Gnedeva • Marianna V. MoldaverYegor E. YegorovAndrey V. Vasiliev •

January 2010

Dermal papilla cells can help form hair-like structures in lab-grown skin cells.

$Human Keratinocytes Derived from the Bulge Region of Hair Follicles Are Refractory to Differentiation$

research Human keratinocytes derived from the bulge region of hair follicles are refractory to differentiation

8 citations , April 2009 in “International journal of oncology”

Hair follicle cells resist turning into skin cells.

research Faculty Opinions recommendation of Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration.

November 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Keratin 79 cells help form and regenerate hair canals.

research Multifaceted role of keratins in epithelial cell differentiation and transformation

50 citations , April 2019 in “Journal of Biosciences”

research Modulation of the differentiated phenotype of keratinocytes of the hair follicle and from epidermis

41 citations , July 1994 in “Journal of Dermatological Science”

Hair follicle cells need complex interactions to fully differentiate.

Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins

research Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins.

356 citations , December 1986 in “The journal of cell biology/The Journal of cell biology”

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

DermaCult Keratinocyte Expansion Medium: A Serum- and BPE-Free Medium Supporting Long-Term Feeder-Free Expansion of Primary Human Epidermal and Pluripotent Stem Cell-Derived Keratinocytes

research 566 DermaCult™ Keratinocyte Expansion Medium, a Serum- and BPE-free Medium Supporting Long-term Feeder-free Expansion of Primary Human Epidermal and Pluripotent Stem Cell-Derived Keratinocytes

November 2022 in “Journal of Investigative Dermatology”

DermaCult™ Keratinocyte Expansion Medium allows human skin cells to grow longer while keeping their ability to develop properly.

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