37 citations
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October 2017 in “Advanced drug delivery reviews” The review suggests that there are various treatments to help restore skin color after severe burns.
4 citations
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November 1981 in “Indian Journal of Dermatology Venereology and Leprology” High-dose calcium pantothenate can reverse grey hair in some cases.
October 2024 in “Journal of Cosmetic Dermatology” Over half of young people in Saudi Arabia experience early gray hair, linked to factors like smoking, stress, and family history.
August 2025 in “Journal of Cosmetic Dermatology” Topical treatments and lasers can improve axillary hyperpigmentation, but no best method is established yet.
2 citations
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April 2016 in “Medical Hypotheses” Antioxidants might help prevent pressure ulcers, but more research is needed to find effective ones.
May 2021 in “Open Access Macedonian Journal of Medical Sciences” People with premature hair graying have an imbalance between harmful and protective molecules in their body, hinting that antioxidants might help.
November 2021 in “CRC Press eBooks” Hair color is determined by melanin and can be affected by genetic conditions like albinism.
78 citations
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August 2014 in “Anais Brasileiros de Dermatologia” New vitiligo treatments focus on controlling immune damage and restoring skin color.
December 2018 in “Dermatologic Surgery” Using a 25% trichloroacetic acid peel improves dermabrasion results in vitiligo surgery.
November 2025 in “International Journal of Biological Macromolecules” This eco-friendly hair dye method improves hair health and color durability.
3 citations
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February 1943 in “The American journal of digestive diseases/American journal of digestive diseases” Riboflavin helps heal bed sores, inositol aids skin diseases, and calcium pantothenate doesn't prevent gray hair.
7 citations
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January 2008 in “Indian Journal of Dermatology” Pigmentary mosaicism causes skin color changes and can affect multiple body systems, but has no cure.
September 2022 in “Frontiers in Medicine” New treatments and drugs show promise for improving skin pigmentation and regeneration.
November 2025 in “Journal of Pharmacy and Pharmacology” PEDF reduces oxidative damage and supports stem cells.
January 2026 in “Figshare” Finasteride can cause melasma, especially in people with darker skin.
8 citations
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July 2001 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” New treatments for vitiligo show promise but still face challenges, especially for hands and feet.
Surgical repigmentation can permanently restore color to white hair in vitiligo patients.
26 citations
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July 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
2 citations
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January 2018 in “International Journal of Advanced Community Medicine” The cream effectively reduces hyperpigmentation and signs of aging without causing skin irritation.
14 citations
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July 2012 in “Journal of the American Academy of Dermatology” Topical tacalcitol ointment can help improve symptoms of EFFC.
48 citations
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May 2021 in “Molecules” Plant extracts from dry flowers can be used as safe, effective dyes in cosmetics, offering skin protection and anti-aging benefits.
10 citations
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January 2010 in “Acta dermato-venereologica” Light therapy can effectively treat vitiligo and hair loss caused by a specific medication.
Iron supplements may reverse premature graying in iron-deficient individuals; ingrown nails are common in diabetics with certain risk factors; topical finasteride may reduce scalp DHT as effectively as oral finasteride; monilethrix treatment is challenging but some medications can help.
13 citations
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October 2015 in “Journal of the European Academy of Dermatology and Venereology” The document concludes that early recognition and appropriate treatment of red scalp, red ear, and red scrotum syndromes can lead to remission.
May 2023 in “Health science reports” Coloring shampoos for gray hair may cause gene mutation, reproductive issues, and skin damage, needing stricter regulation and expert consultation.
July 2024 in “Journal of Investigative Dermatology” Topical sulforaphane reduces pigmentation and wrinkles from sun damage.
September 2024 in “Vietnam Journal of Biotechnology” Astaxanthin may help protect hair cells from damage and prevent hair loss.
2 citations
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March 2018 in “The Journal of Dermatology” The "color-transition sign" helps tell apart alopecia areata incognita from telogen effluvium by looking at hair color changes.
16 citations
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January 2013 in “Internal Medicine” Early hair whitening may indicate a higher risk of heart disease in young and middle-aged men.
February 2013 in “Journal of the American Academy of Dermatology” Iron supplements may reverse premature hair graying caused by iron deficiency.