48 citations
,
October 2014 in “International Journal of Cardiology” People with alopecia are at higher risk for heart disease and have more heart-related risk factors.
47 citations
,
March 2017 in “Clinical, cosmetic and investigational dermatology” Certain skin conditions may indicate or increase the risk of Parkinson's disease.
46 citations
,
November 1997 in “Journal of Neural Transmission” Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.
45 citations
,
June 2012 in “JRSM Cardiovascular Disease” Young Indians with coronary artery disease often have risk factors like smoking and central obesity, and cutaneous markers should be monitored for lifestyle changes.
45 citations
,
February 2012 Obese women with PCOS are more likely to have fatty liver disease.
41 citations
,
May 2020 in “Frontiers in immunology” Hidradenitis suppurativa might be a type of autoinflammatory skin disease.
41 citations
,
July 2018 in “Frontiers in Neurology” Myotonic dystrophy may be classified as a segmental progeroid disorder.
41 citations
,
January 2012 in “Journal of Korean Medical Science” Over 60% of Korean military personnel had skin diseases, commonly acne and athlete's foot, linked to service length and stress.
40 citations
,
November 2019 in “Frontiers in Endocrinology” Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.
40 citations
,
January 2017 in “Intestinal Research” Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.
40 citations
,
November 2013 in “European journal of endocrinology” Effective hirsutism treatment for women with PCOS should be personalized and may include lifestyle changes and medication.
40 citations
,
October 2012 in “Journal of the American Academy of Dermatology” CLASI is a valid tool for assessing skin activity and damage in lupus patients.
38 citations
,
September 2014 in “Cell and Tissue Research” The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
37 citations
,
January 2005 in “Dermatology Online Journal” Women under 55 with hair loss (AGA) may have a higher risk of heart disease (CAD).
36 citations
,
May 2025 in “Antioxidants” Lipid peroxidation worsens skin diseases but may help treat cancer.
35 citations
,
January 2022 in “Clinical Infectious Diseases” Healthcare workers with COVID-19 reported more long-term symptoms, and physical activity may help reduce some of these symptoms.
35 citations
,
May 2015 in “Arquivos De Gastroenterologia” Women with PCOS are more likely to have fatty liver disease and worse metabolic health.
34 citations
,
July 2020 in “Frontiers in immunology” Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.
34 citations
,
October 2011 in “Pathology Research International” Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.
33 citations
,
January 2018 in “Blood” Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.
33 citations
,
November 2012 in “JAMA Dermatology” Most women with weird scalp feelings had neck spine problems, and some got better with gabapentin treatment.
33 citations
,
June 2012 in “Journal of Crohn's and colitis” Alopecia Areata might be linked to Crohn's disease.
32 citations
,
February 2016 in “The American journal of dermatopathology/American journal of dermatopathology” Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.
32 citations
,
March 2015 in “The Journal of Clinical Endocrinology & Metabolism” Alopecia areata is linked to thyroid autoimmunity but not type 1 diabetes.
32 citations
,
August 2003 in “Journal of the European Academy of Dermatology and Venereology” cGVHD often severely affects the skin, causing rapid aging and other issues.
30 citations
,
November 2024 in “ACS Materials Au” Microneedles are promising for disease monitoring and drug delivery due to their minimal invasiveness and versatility.
30 citations
,
May 2015 in “Current Cardiology Reviews” Lower testosterone increases heart disease risk; higher estradiol increases risk in women.
29 citations
,
June 2020 in “International Journal of Molecular Sciences” Notch signaling disruptions can cause various skin diseases.
29 citations
,
June 2017 in “Journal of Inherited Metabolic Disease” High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
28 citations
,
June 2021 in “Frontiers in immunology” A protein called lfTSLP is important in causing allergic and other skin diseases and could be a target for treatment.