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research Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds

301 citations , February 2019 in “Nature Communications”

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

research Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival

237 citations , February 2016 in “Science Translational Medicine”

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

research Conditional Disruption of Hedgehog Signaling Pathway Defines its Critical Role in Hair Development and Regeneration

194 citations , May 2000 in “Journal of Investigative Dermatology”

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

ATP-Competitive mTOR Kinase Inhibitors Delay Plant Growth by Triggering Early Differentiation of Meristematic Cells Without Developmental Patterning Change

research ATP-competitive mTOR kinase inhibitors delay plant growth by triggering early differentiation of meristematic cells but no developmental patterning change

161 citations , August 2013 in “Journal of experimental botany”

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

research Early inductive events in ectodermal appendage morphogenesis

160 citations , January 2014 in “Seminars in cell & developmental biology”

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation

research Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation

115 citations , August 2008 in “The Journal of Clinical Endocrinology & Metabolism”

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

research Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis

106 citations , October 2016 in “Cell Stem Cell”

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

research Quantitative Single-Cell Approaches to Stem Cell Research

106 citations , November 2014 in “Cell Stem Cell”

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

research Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis

102 citations , August 2008 in “Genes & Development”

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

research Evaluation and diagnosis of the hair loss patient

86 citations , August 2014 in “Journal of The American Academy of Dermatology”

To diagnose hair loss, use a systematic approach including history, exams, and tests.

research The Peripheral Clock Regulates Human Pigmentation

81 citations , October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology”

Certain genes control the color of human hair by affecting pigment production.

Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes

research Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes

81 citations , September 2005 in “The American journal of pathology”

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

Activation of Cytoprotective Prostaglandin Synthase-1 by Minoxidil as a Possible Explanation for Its Hair Growth-Stimulating Effect

research Activation of Cytoprotective Prostaglandin Synthase-1 by Minoxidil as a Possible Explanation for Its Hair Growth-Stimulating Effect

81 citations , February 1997 in “Journal of Investigative Dermatology”

Minoxidil boosts hair growth by activating PGHS-1.

research Human hair follicles are an extrarenal source and a nonhematopoietic target of erythropoietin

71 citations , May 2007 in “The FASEB journal”

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

research A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease

67 citations , November 2019 in “Nature Communications”

Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.

research Oxidative Damage Control in a Human (Mini-) Organ: Nrf2 Activation Protects against Oxidative Stress-Induced Hair Growth Inhibition

58 citations , October 2016 in “Journal of Investigative Dermatology”

Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.

research Diagnosis and Management of Alopecia in Children

51 citations , January 2014 in “Pediatric Clinics of North America”

The guide explains how to identify and treat children's hair loss, including fungal infections, autoimmune disorders, hairstyle changes, self-correcting conditions, and behavioral therapy for hair-pulling.