research Androgens and acne: perspectives on clascoterone, the first topical androgen receptor antagonist
Clascoterone is a new, effective, and safe acne treatment without systemic side effects.
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research Issue Information
The document summarized various dermatology studies and case reports.
research Evaluation of New Pregnane Derivatives as 5.ALPHA.-Reductase Inhibitor.
New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
research Formulation and evaluation of repurposed ketoconazole‐loaded transferosomal gel for enhanced trichogenic effects
The ketoconazole gel improved hair growth and is a promising treatment for hair loss.
research 60058 Change in patient-reported hair satisfaction during deuruxolitinib treatment of severe alopecia areata: Pooled data from the Phase 3 THRIVE-AA1 and THRIVE-AA2 trials
Deuruxolitinib significantly improves hair satisfaction in severe alopecia areata patients.
research Vitamin E TPGS based transferosomes augmented TAT as a promising delivery system for improved transdermal delivery of raloxifene
The new delivery system improved raloxifene's skin absorption and effectiveness against cancer cells.
research Equine 5α-reductase activity and expression in epididymis
The equine epididymis mainly uses type 1 5α-reductase, and both finasteride and dutasteride can inhibit its activity.
research Compatibility of Different Formulations in TrichoConceptTM Vehicles for Hair Treatments
Different hair loss treatment ingredients work well with TrichoTech™ vehicles for 3 to 6 months, making them good for use in hair treatments.
research Diphenylcyclopropenone Treatment Outcomes for Alopecia Areata
Diphenylcyclopropenone is effective for treating alopecia areata but has a high relapse rate.
research Ethosome as a potential transdermal drug delivery system
Ethosomes are a promising way to deliver drugs through the skin.
research Role of Topical Ketoconazole in Therapeutic Hair Care Beyond Seborrhoeic Dermatitis and Dandruff
Ketoconazole shampoo may help reduce hair loss and improve hair health.
research 51840 Efficacy of the Oral JAK1/JAK2 Inhibitor Deuruxolitinib in Adult Patients with Moderate to Severe Alopecia Areata: Pooled Results from the Multinational Double-Blind, Placebo-Controlled THRIVE-AA1 and THRIVE-AA2 Phase 3 Trials
Deuruxolitinib significantly helps regrow scalp hair in adults with moderate to severe alopecia areata.
research Metabolic study of androsta-1,4,6-triene-3,17-dione in horses using liquid chromatography/high resolution mass spectrometry
The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.
research An Interventional, Comparative, Prospective Study to Determine Optimum Concentration of Intralesional Triamcinolone Acetonide in Treatment of Alopecia Areata
2.5 mg/ml of triamcinolone acetonide is more effective for treating alopecia areata.
research Minoxidil and Dexamethasone Eluting Nanofiber Dressing for Cutaneous Wound Healing in Rat
The new wound dressing with minoxidil and dexamethasone could speed up healing and reduce scarring in rats.
research An Assessment of the Safety, Efficacy, and Tolerability of a Novel Scalp Treatment Regimen Combining a Hydroxy Acid-Based Scrub and Copper Tripeptide Serum in the Management of Seborrheic Dermatitis in Adults
The treatment safely and effectively reduces dandruff and improves scalp health.
research 2-Substituted 4-(Thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
research Non-invasive analysis of penetration and storage of Isoconazole nitrate in the stratum corneum and the hair follicles
Isoconazole nitrate stays effective in skin and hair follicles for up to two weeks after use.
research Effect of Dieckol, a Component of Ecklonia cava, on the Promotion of Hair Growth
Dieckol from Ecklonia cava may help hair growth and could be a potential hair loss treatment.
research TREATMENT FOR ULERYTHEMA OPHRYOGENES WITH HYDROCORTISONE OINTMENT
Hydrocortisone ointment effectively improved eyebrow skin and hair in a 10-year-old.
research Clinical Outcome of the Topical Application of a Novel Hair Growth Ingredient, USPlus DERM, in Men and Women
The saw palmetto serum improved hair growth and reduced hair loss and dandruff.
research Θειική δεϋδροεπιανδροστερόνη, αντίσταση στην ινσουλίνη και εκτίμηση του όγκου των ωοθηκών σε Ελληνίδες με σύνδρομο πολυκυστικών ωοθηκών (PCOS)
Higher DHEA-S levels are linked to smaller ovarian volume in women with PCOS.
research Supratherapeutic Vitamin D with a Hair Nutraceutical: A Case Report
research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
research An ophthalmological and electroretinographic study of patients taking canthaxanthin and beta-carotene
Long-term use of canthaxanthin may cause reversible changes in the eye, including crystal deposits and altered vision responses.
research Spironolactone in combination drug therapy for unresponsive hirsutism
Combination drug therapy is effective for hirsutism that doesn't improve with just one medication.
research Core-shell and core-amphiphilic branched shell nanocarriers based on biodegradable hyperbranched polymers, as potential drug delivery systems
The new biodegradable nanocarriers safely and effectively deliver drugs into the skin.
research Synthesis and 5α-Reductase Inhibitory Activity of C21 Steroids Having 1,4-diene or 4,6-diene 20-ones and 4-Azasteroid 20-Oximes
Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.
research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors
Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.