118 citations
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April 2020 in “Stem Cell Research & Therapy” IFNγ-primed MSC secretomes can improve joint health by reducing inflammation and supporting tissue repair.
105 citations
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October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
67 citations
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May 2014 in “International Journal of Molecular Sciences” Using your own skin cells can help repair aging skin and promote hair growth.
54 citations
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January 2009 in “Development” β-catenin, Shh, and Bmp signaling control hair follicle development.
51 citations
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August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
39 citations
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August 2017 in “Annual Review of Genetics” Understanding tissue regeneration in animals can improve regenerative medicine.
31 citations
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August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
31 citations
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September 2012 in “Journal of biological chemistry/The Journal of biological chemistry” The right amount of retinoic acid is essential for normal hair growth and development.
29 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
27 citations
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February 2023 in “Frontiers in Cell and Developmental Biology” WNT10B is important for body functions and linked to diseases like osteoporosis, obesity, and cancer.
25 citations
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June 2022 in “Developmental cell” Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
22 citations
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June 2024 in “Cell” Understanding tissue self-organization can improve treatments for diseases and advance regenerative medicine.
21 citations
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July 2018 in “International Journal of Molecular Sciences” Foxn1 is crucial for skin development and healing, and altering its expression may aid regenerative medicine.
19 citations
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August 2024 in “Journal of Translational Medicine” Epidermal stem cells are vital for skin healing and have potential for treating skin disorders.
17 citations
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May 2018 in “BMC genomics” Researchers found genes and microRNAs that control curly fleece in Chinese Tan sheep.
16 citations
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April 2021 in “Frontiers in Cell and Developmental Biology” New hair follicles could be created to treat hair loss.
15 citations
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July 2024 in “Current Issues in Molecular Biology” Understanding molecular processes in skin development is key to creating targeted treatments for skin disorders.
13 citations
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September 2014 in “BMC Complementary and Alternative Medicine” Tanshinone IIA helps protect skin tissue from low oxygen damage by boosting certain cell markers.
12 citations
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January 2009 in “Stembook” Improved understanding of stem cell mechanisms can enhance skin tissue engineering.
9 citations
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August 2025 in “Current Issues in Molecular Biology” Extracellular vesicles can help regenerate bones but need more research for safe clinical use.
9 citations
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June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
9 citations
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February 2022 in “BMC Genomics” Melatonin affects gene expression in goat hair follicles, potentially increasing cashmere production.
9 citations
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February 2021 in “Frontiers in Cell and Developmental Biology” Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
8 citations
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October 2022 in “International Journal of Molecular Sciences” Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.
7 citations
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December 2021 in “Pharmaceutics” Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.
6 citations
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November 2022 in “Development” New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.
6 citations
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October 2014 in “International Journal of Molecular Sciences” Tanshinone IIA helps protect tissue from low oxygen damage by activating certain cell pathways.
5 citations
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January 2024 in “Reproductive Medicine and Biology” Androgen and Wnt signals are crucial for developing and functioning male genitalia and erectile tissues.
5 citations
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October 2021 in “Frontiers in Cell and Developmental Biology” Fat tissue under the skin affects hair growth and aging; reducing its inflammation may help treat hair loss.
5 citations
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September 2021 in “Frontiers in Cell and Developmental Biology” Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.