56 citations
,
February 2010 in “PLOS ONE” Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
78 citations
,
May 2019 in “Frontiers in Cellular and Infection Microbiology” DPK-060 in poloxamer gel effectively treats skin infections, but nanocarriers don't enhance its efficacy.
19 citations
,
December 2015 in “Journal of Materials Chemistry B” Scientists have created a method to deliver specific cells that can regenerate hair follicles, potentially offering a new treatment for hair loss.
31 citations
,
October 2010 in “BMB Reports” L-threonate may help prevent balding by blocking a key protein.
December 2015 in “OPAL (Open@LaTrobe) (La Trobe University)” QLT0267 stops hair follicle cell growth and movement.
15 citations
,
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.
8 citations
,
November 2024 in “Acta Dermato Venereologica” The Dermatology Life Quality Index is reliable and consistent but needs more diverse participant studies.
17 citations
,
September 2018 in “Matrix Biology” Laminin-511 is essential for proper melanocyte movement and development in mice.
2 citations
,
October 2010 in “BMB Reports” L-threonate may help prevent balding by blocking a key hair loss factor.
September 2023 in “Nature communications” Alk1 in specific cells is crucial for proper nerve branching and hair function.
2 citations
,
July 2015 in “Case Reports in Dermatology” DDS treatment for LABD can cause severe side effects like anemia and hair loss, requiring careful monitoring.
August 2025 in “International Journal of Contemporary Pediatrics” HLD10 can include increased body hair and Mongolian spots.
Poly-D,L-lactic acid boosts hair growth in aged skin by activating hair follicle stem cells.
9 citations
,
May 2012 in “PLOS ONE” ILK is essential for skin development, pigmentation, and healing.
February 2026 in “International Journal of Molecular Sciences” PDLLA filler can improve hair thickness and shine by reducing age-related hair decline.
Lhx2 helps retinal cells respond to signals for eye development.
Plakophilin 1 helps control skin cell immune responses to prevent excessive inflammation.
126 citations
,
August 2018 in “Molecular Systems Biology” Fibroblast state switching is crucial for skin healing and development.
46 citations
,
November 2007 in “Gene Expression Patterns” Trps1 plays a key role in hair follicle development and cycling.
44 citations
,
June 2023 in “Cell Reports” IL-1 promotes fat cell growth in skin, while WNT inhibits it and encourages scar formation.
19 citations
,
February 2022 in “Journal of Investigative Dermatology” Mechanical stretching can improve or hinder skin regeneration depending on duration.
1 citations
,
August 2023 in “The Journal of Pathology” Different types of skin fibroblasts have unique roles in skin health and disease.
11 citations
,
September 2010 in “PubMed” DHA-NLC may improve drug delivery and reduce side effects for cancer treatment.
June 2026 in “British Journal of Dermatology” A 24-year-old woman developed lichen planopilaris (LPP), a type of scarring alopecia, after undergoing hairline-lowering surgery (HLS) for cosmetic reasons. Despite having no prior history of hair disorders, she experienced acute hair shedding and patchy hair loss post-surgery. A biopsy confirmed LPP, and treatment stabilized her condition. This case is the first reported instance of LPP following HLS, suggesting that surgical trauma may trigger LPP in predisposed individuals through mechanisms like the Koebner phenomenon and immune responses. The incidence and risk factors for LPP after HLS remain unknown.
April 2018 in “Journal of Investigative Dermatology” Dsg1 is essential for maintaining a healthy skin barrier in mice.
6 citations
,
December 2021 in “Journal of Clinical Medicine” LiPADI is a useful tool for monitoring the severity and treatment of lichen planus.
102 citations
,
August 2008 in “Genes & Development” Laminin-511 is crucial for early hair growth and maintaining important hair development signals.
May 2024 in “Indian journal of pharmacy and pharmacology” Luliconazole is more effective than ketoconazole at repairing damaged hair cuticles.
6 citations
,
September 2018 in “Journal of Dermatological Treatment” LLLT devices for hair loss need more research to define proper guidelines.
April 2017 in “Journal of Investigative Dermatology” Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.