Search

for
Search:

Sort by

Research

570-600 / 1000+ results

research 312 CRISPR/Cas9-based targeted genome editing for correction of recessive dystrophic epidermolysis bullosa using iPS cells

1 citations , September 2019 in “Journal of Investigative Dermatology”

The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.

research Advances in the genetic understanding of hypohidrotic ectodermal dysplasia

1 citations , November 2017 in “Expert opinion on orphan drugs”

Scientists now better understand the genetics of hypohidrotic ectodermal dysplasia, leading to more accurate diagnoses and potential new treatments.

research FGF signaling for hair cycle resting phase alleviates radiation alopecia

1 citations , September 2016 in “Journal of Dermatological Science”

FGF18 treatment during hair's resting phase can protect against hair loss from radiation.

research The Experimental Studies of YangHyulEum Gami-Bang Extracts on the Hair Growth Effect

1 citations , August 2016 in “Hanbang an'i'bi'in'hu pibu'gwa haghoeji”

YangHyulEum Gami-Bang extract may help treat hair loss.

research Montagna Symposium 2013—Light and Skin: How Light Sustains, Damages, Treats, Images and Modifies Skin Biology

1 citations , July 2014 in “The journal of investigative dermatology/Journal of investigative dermatology”

Light affects skin health, aging, and cancer risk, and new light-based treatments and imaging are promising for skin care.

research Epigenetic modifications may explain the relative protection of occipital hair follicles from androgenetic alopecia in men

1 citations , July 2011 in “Hair transplant forum international”

Epigenetic changes might protect occipital hair from male pattern baldness.

research Hair: Microscopic Analysis

1 citations , April 2009 in “Wiley Encyclopedia of Forensic Science”

Microscopic hair analysis helps identify species and sometimes individuals in forensic science.

research The detection of apoptosis and bcl₂ in isolated secondary mohair follicles (growing and quiescent), cultured in vitro in the presence or absence of biotin

1 citations , January 1999 in “Proceedings of the British Society of Animal Science”

Biotin helps maintain hair follicle growth by affecting cell death and survival signals.

research Application of multi-omics techniques to androgenetic alopecia: Current status and perspectives

June 2024 in “Computational and Structural Biotechnology Journal”

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.

research Progress in Research and Prospects for Application of Precision Gene-Editing Technology Based on CRISPR–Cas9 in the Genetic Improvement of Sheep and Goats

March 2024 in “Agriculture”

CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.

research The role of Extracellular Vesicles in Alopecia and its Treatment

February 2022

Extracellular vesicles could help treat hair loss by influencing hair growth cycles.

research Transforming 300 billion points of data into diagnostics, therapeutics and new insights into disease

June 2013 in “The mental health clinician”

Large data can lead to new medical discoveries and personalized medicine.

research Medical Management Options for Hair Loss

July 2011 in “Springer eBooks”

The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.

research Pediatric Endocrine-Disrupting Chemical Exposure Produces Irreversible Organizational Injury: Biomarker Evidence Necessitating a Precautionary Public Health Framework

June 2026 in “Scholarly review .”

Endocrine-disrupting chemicals cause irreversible harm to children's development, increasing disease risk.

research SÍNDROME PÓS-FINASTERIDA E O IMPACTO DOS INIBIDORES DA 5-ALFA REDUTASE NOS EIXOS NEUROENDÓCRINO E METABÓLICO

May 2026 in “RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218”

This review analyzes recent scientific evidence on the neuroendocrine and metabolic impacts of chronic use of 5-alpha reductase inhibitors, focusing on Post-Finasteride Syndrome (PFS). The study, based on eight high-impact studies from 2021 to 2026, highlights PFS as a multisystemic condition linked to the use of 5-ARIs, with reports of refractory sexual dysfunction and mood disorders in young patients. The inhibition of enzymes in the central nervous system suppresses the synthesis of active metabolites like allopregnanolone, leading to GABAergic dysregulation and excitotoxicity. Metabolically, the suppression of dihydrotestosterone is associated with insulin resistance, non-alcoholic fatty liver disease, Type 2 Diabetes Mellitus, and changes in gut microbiota. Genetic polymorphisms in the SRD5A2 gene and epigenetic changes, such as DNA methylation of the androgen receptor, contribute to the chronicity of symptoms. The findings suggest that PFS extends beyond transient side effects, emphasizing the need for personalized medicine models and strengthened informed consent protocols to mitigate persistent biopsychosocial risks.