research Protective effect of DA-9401 in finasteride-induced apoptosis in rat testis: inositol requiring kinase 1 and c-Jun N-terminal kinase pathway
DA-9401 helps protect rat testis from finasteride damage.
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research Minoxidil: a review of its pharmacological properties and therapeutic use.
Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.
research Social Interest Data as a Proxy for Off-Label Performance-Enhancing Drug Use: Implications and Clinical Considerations
Clinicians should use social and prescription data to track trends in performance-enhancing drug use.
research Control plasma renin activity and changes in sympathetic tone as determinants of minoxidil-induced increase in plasma renin activity.
Minoxidil boosts plasma renin activity, influenced by control plasma renin activity and changes in sympathetic tone.
research Computational Evaluation of Dibenzo Compounds as Potential Dual Inhibitors of Androgen Receptor and 5α-Reductase
Some dibenzo compounds might help treat cancer with fewer side effects.
research Potassium channels: new targets for drug treatment.
Potassium channels are important drug targets for treating conditions like hypertension, hair loss, and diabetes.
research Deoxycorticosterone’s anticonvulsant effects in infant rats are blocked by finasteride, but not by indomethacin
Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.
research Allopregnanolone, the active metabolite of progesterone protects against neuronal damage in picrotoxin-induced seizure model in mice
research Dutasteride nanocapsules for hair follicle targeting: Effect of chitosan-coating and physical stimulus
Chitosan-coated dutasteride nanocapsules improve hair treatment, and physical stimulation boosts effectiveness.
research Neuroactive steroids induce changes in fetal sheep behavior during normoxic and asphyxic states
Neurosteroids help protect fetal brains from asphyxia damage.
research Influence of the alkylsulfonylamino substituent located at the 6-position of 2,2-dimethylchromans structurally related to cromakalim: From potassium channel openers to calcium entry blockers?
New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
research Reporting on Adverse Clinical Events
Different medications can cause serious side effects in some people.
research 5α-Reductase inhibitors alter steroid metabolism and may contribute to insulin resistance, diabetes, metabolic syndrome and vascular disease: a medical hypothesis
Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
research Blockbuster Weight-Loss Drugs Not Tied to Suicidality, Studies Show
Weight-loss drugs are not linked to suicidal thoughts.
research Pharmacological aspects of hair follicle growth
Minoxidil and 4-MA can help treat hair loss.
research α‐Difluoromethylornithine, a polyamine inhibitor: its potential role in controlling hair growth and in cancer treatment and chemo‐prevention
DFMO may help control hair growth and treat cancer.
research 5α-Reductase inhibitors, antiviral and anti-tumor activities of some steroidal cyanopyridinone derivatives
Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.
research Metformin/dopamine derived bioactive carbon dots accelerate bacteria‐infected wound healing
Metformin/dopamine-derived carbon dots help heal bacteria-infected wounds faster.
research Udenafil Induces the Hair Growth Effect of Adipose-Derived Stem Cells
Udenafil may help hair grow by activating certain stem cells.
research 187 Protective Effect of DA-9401 on Acute use of Finasteride on Sprague–Dawley Rats
DA-9401 protects against hair loss, improves organ function, and prevents infertility caused by finasteride.
research Induction of ornithine decarboxylase in specific subpopulations of murine epidermal cells following multiple exposures to 12-O-tetradecanoylphorbol-13-acetate, mezerein and ethyl phenylpropriolate
TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.
research Drug-induced hair colour changes
Some medications can cause rare hair color changes, and reporting these side effects is important for patient quality of life.
research Clinical Analysis of Parkinson's Disease with Urinary Bladder Dysfunction:A Report of 64 Cases
Proper treatments based on tests can improve life quality and protect kidneys in Parkinson's patients with bladder issues.
research Reduced metabolites mediate neuroprotective effects of progesterone in the adult rat hippocampus. The synthetic progestin medroxyprogesterone acetate (Provera) is not neuroprotective
Progesterone protects brain cells, but Provera does not.
research Biochemical features of primary cells from a pediatric patient with a gain-of-function ODC1 genetic mutation
A new genetic disorder caused by an ODC1 mutation can be treated with DFMO.
research Insights learned from L457(3.43)R, an activating mutant of the human lutropin receptor
The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.
research Selective Sensing of Darolutamide and Thalidomide in Pharmaceutical Preparations and in Spiked Biofluids
A new, efficient method has been developed to detect darolutamide and thalidomide, drugs used for certain hair loss and prostate cancer treatments, in pharmaceuticals and body fluids.
research Supramolecular Adenosine-Based Skin Delivery System for Hair Regulation and Restoration
TA-Ado effectively promotes hair growth and reduces hair loss.
research Melatonin-Loaded Nanoparticles for Enhanced Antidepressant Effects and HPA Hormone Modulation
Melatonin-loaded nanoparticles improve antidepressant effects and HPA hormone balance better than regular melatonin.
research Host-Directed FDA-Approved Drugs with Antiviral Activity against SARS-CoV-2 Identified by Hierarchical In Silico/In Vitro Screening Methods
Five FDA-approved drugs may help block COVID-19 virus entry.