research Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance
Repurposing existing drugs and using micronutrients may effectively target cancer stem cells and improve cancer treatment.
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90-120 / 727 resultsresearch Two Opposing Faces of Retinoic Acid: Induction of Stemness or Induction of Differentiation Depending on Cell-Type
Retinoic acid can either maintain stem cells or make them specialize, depending on the cell type.
research Characterization of Human Dermal Papilla Cells in Alginate Spheres
Alginate spheres help maintain hair growth potential in human cells for hair loss treatment.
research TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
research ECM1 modified HF-MSCs targeting HSC attenuate liver cirrhosis by inhibiting the TGF-β/Smad signaling pathway
ECM1-modified stem cells can effectively treat liver cirrhosis.
research Hair regeneration: Mechano-activation and related therapeutic approaches.
Mechanical stimulation and new therapies show promise for hair regrowth.
research Advancing Regenerative Cellular Therapies in Non-Scarring Alopecia
Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.
research Rejuvenation: an integrated approach to regenerative medicine
Rejuvenating self-repair mechanisms could improve organ recovery in regenerative medicine.
research Recent Advances in Drug Development for Hair Loss
New treatments for hair loss show promise with advanced therapies and better targeting.
research Biomedical applications of electrospun nanofibers in the management of androgenic alopecia
Electrospun nanofibers might be a promising new treatment for hair loss.
research Deciphering the Mesodermal Potency of Porcine Skin-Derived Progenitors (SKP) by Microarray Analysis
Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
research Industry Report
The regenerative medicine industry saw business growth with new partnerships, clinical trials, and financial investments.
research Wnt Signaling and Aging-Related Heart Disorders
Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.
research The regulation of skin homeostasis, repair and the pathogenesis of skin diseases by spatiotemporal activation of epidermal mTOR signaling
Proper mTOR signaling is crucial for healthy skin and preventing skin diseases.
research Decision letter: Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γ
Loss of Dnmt3a and Dnmt3b increases aggressive skin tumors by affecting PPAR-γ.
research Dermal TRPV1 innervations engage a macrophage- and fibroblast-containing pathway to activate hair growth in mice
Activating TRPV1 can boost hair growth by involving neurons, macrophages, and fibroblasts.
research In vitro and clinical evaluation of umbilical cord‐derived mesenchymal stromal cell‐conditioned media for hair regeneration
Umbilical cord-derived media is safe and effective for hair growth.
research An ear punch model for studying the effect of radiation on wound healing
Radiation significantly slows down wound healing in mice.
research Recent progress in the effect of ferroptosis of HSCs on the development of liver fibrosis
Inducing ferroptosis in hepatic stellate cells is crucial for treating liver fibrosis.
research TGFβ and cancer metastasis: an inflammation link
TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
research Progress on mitochondria and hair follicle development in androgenetic alopecia: relationships and therapeutic perspectives
Maintaining healthy mitochondria may help treat hair loss.
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
research Biomimetic Scaffolds—A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering
Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.
research Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time
Advanced imaging methods have improved understanding of cancer cell interactions and treatment strategies.
research Understanding human aging and the fundamental cell signaling link in age-related diseases: the middle-aging hypovascularity hypoxia hypothesis
Improving blood flow and oxygen levels in middle age may help prevent age-related diseases.
research LSD1 is Required for Hair Cell Regeneration in Zebrafish
LSD1 is crucial for regenerating hair cells in zebrafish.
research Clinical perspectives on the age-related increase of immunosuppressive activity
Aging and chronic inflammation weaken the immune system, increasing cancer and infection risks.
research Platelet-Rich Plasma for Hair Loss
Platelet-Rich Plasma (PRP), a protein-rich extract from a patient's blood, shows promise in improving hair density, thickness, and quality, but the best method of use and number of treatments needed for noticeable results are still unclear.
research The effect of active hexose correlated compound in modulating cytosine arabinoside-induced hair loss, and 6-mercaptopurine- and methotrexate-induced liver injury in rodents
AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.
research The regenerative potential of skin and the immune system
The skin's immune system helps it regenerate and fight infections.