363 citations
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May 2006 in “Current Opinion in Psychiatry” Anorexia and bulimia lead to serious health problems and increased risk of death, requiring aggressive treatment.
359 citations
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January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
269 citations
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May 2002 in “Journal of Neuroscience” Stress increases neurosteroids that help prevent seizures.
201 citations
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November 1964 in “Journal of neurophysiology” The cuneate nucleus has two main neuron types: relay neurons and interneurons.
150 citations
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June 2014 in “Biomaterials” Peptide hydrogels heal burn wounds faster and better than standard dressings.
140 citations
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December 2017 in “Journal of Controlled Release” Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
138 citations
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June 2019 in “Stem Cells and Development” Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.
135 citations
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December 2015 in “Expert Opinion on Biological Therapy” Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
132 citations
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July 2000 in “Lupus” In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.
131 citations
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July 2009 in “Experimental Dermatology” The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.
131 citations
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November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.
114 citations
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February 2012 in “International Journal of Dermatology” Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
113 citations
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November 2017 in “Scientific Reports” Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
113 citations
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September 2005 in “Journal of Investigative Dermatology” Applying a special compound can promote hair growth without harmful side effects.
86 citations
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March 2018 in “ACS Biomaterials Science & Engineering” MDP hydrogel heals wounds faster and better than other treatments in diabetic mice.
81 citations
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January 2011 in “European Journal of Internal Medicine” Despite progress, better treatments and understanding are needed for the high rates of long-term issues and deaths linked to eating disorders.
80 citations
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June 2020 in “Dermatopathology” COVID-19 can cause various skin lesions, which may result from the virus and immune response, and are not directly linked to illness severity.
67 citations
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December 2009 in “Stem Cells” β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.
66 citations
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March 2019 in “Cellular and Molecular Life Sciences” Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
64 citations
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July 2016 in “Journal of Immunology” Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.
64 citations
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January 2002 in “American Journal of Clinical Dermatology” Some patients taking antipsychotic medications experience skin reactions, ranging from mild to severe.
60 citations
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September 2010 in “Journal of the American Academy of Dermatology” Small white dots on the scalp seen with a dermoscope correspond to sweat ducts and vary with different hair disorders.
59 citations
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September 2008 in “Experimental dermatology” Both mouse and rat models are effective for testing alopecia areata treatments.
58 citations
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February 2016 in “Scientific reports” Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
54 citations
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November 2015 in “Methods in enzymology on CD-ROM/Methods in enzymology” Keratins are important for skin cell health and their problems can cause diseases.
53 citations
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September 1999 in “The journal of cell biology/The Journal of cell biology” K16 can partially replace K14 but causes hair loss and skin issues.
53 citations
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November 1992 in “Mayo Clinic Proceedings” HIV can cause unusual and severe skin problems that are hard to treat.
52 citations
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October 2016 in “Clinics in Dermatology” Some medications can cause acne, and stopping these drugs is the main treatment.
50 citations
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October 1918 in “The journal of experimental zoology” Artificially inducing hair regrowth in mice can change the normal pattern and timing of hair growth, with minimal color differences between old and new fur.
48 citations
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February 2025 in “Nano-Micro Letters” Microneedles offer a promising, painless way to treat skin diseases but need improvements for better use.