3 citations
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August 2015 in “Acta Scientiarum Biological Sciences” Neem extract is safe for pregnant or lactating rats at tested doses.
2 citations
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May 2016 in “Journal of Clinical Oncology” Topical calcitriol may reduce hair loss from chemotherapy at higher doses.
1 citations
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May 2024 in “Dermatology Online Journal” Scalp pemphigus vulgaris can be effectively treated with low-dose prednisone and triamcinolone.
1 citations
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January 2021 in “Skin appendage disorders” A woman with alopecia regrew her hair after taking a higher dose of tocilizumab.
1 citations
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May 2001 in “Pharmacology & Toxicology” Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.
January 2026 in “Journal of Radiation Research” 53BP1 focus analysis in hair cells can help estimate radiation doses.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Ficus platyphylla leaf extract is likely safe in high doses, with minor temporary side effects.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Ficus platyphylla leaf extract is likely safe in high doses for rats.
Finasteride improves hair but may reduce sperm quality at higher doses.
May 2025 in “Birth Defects Research” YWS1903 is safe for pregnant rats at moderate doses but causes fetal issues at high doses.
February 2025 in “Biomolecules” Melatonin can help or hinder hair growth depending on the dose.
March 2024 in “Journal of medicinal plants studies” Hibiscus has medicinal benefits but can be toxic in high doses and is unsafe for pregnant women and infants.
May 2023 in “JAMA network open” After a New York Times article talked about using low-dose oral minoxidil for hair loss, more people started getting this drug prescribed, but this trend didn't last long.
September 2019 in “Hair transplant forum international” The study looked at the effects of any dose of finasteride, not a specific amount.
January 2017 in “UiTM Institutional Repositories (Universiti Teknologi MARA)” Hibiscus rosa-sinensis leaf extract is safe for mice at tested doses.
November 2020 in “Journal of The American Academy of Dermatology” Finasteride 1 mg every other month works as well as daily dose for hair loss maintenance.
August 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” Finasteride, at doses of 5mg or higher, may negatively affect male fertility by reducing the expression of certain genes involved in sperm production.
December 1989 in “Inpharma (Balgowlah)” Cyproterone helps women with hair loss caused by genetics. More research is needed to confirm the best dose.
Flutamide effectively treats female pattern hair loss long-term with low doses being safe for the liver.
1108 citations
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January 2018 in “Dalton transactions” Platinum-based chemotherapy drugs can cause many severe side effects, often requiring dose reductions and additional medications to manage.
284 citations
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November 1999 in “Neurology” The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.
81 citations
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February 2000 in “Anti-cancer drugs” Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.
67 citations
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February 1997 in “Teratology” Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.
52 citations
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February 2003 in “Archives of dermatology” 9-cis-retinoic acid showed some effectiveness in treating AIDS-related Kaposi sarcoma but had significant side effects at higher doses.
43 citations
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January 1977 in “Toxicology and Applied Pharmacology” Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.
24 citations
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July 1979 in “Archives of Dermatology” Patients with renal disease may develop vitamin A toxicity even with low-dose supplements.
23 citations
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January 2018 in “International Journal of Dermatology” Oral isotretinoin, especially at higher doses for at least 3 months, is effective for treating folliculitis decalvans.
20 citations
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September 1983 in “Archives of dermatology” The new synthetic retinoid RO 13-6298 effectively treated severe psoriasis at low doses with manageable side effects.
19 citations
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January 2009 in “Journal of Young Pharmacists” Alcoholic extract of Eclipta alba may help treat allergies and is safe at high doses.
19 citations
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January 2009 in “OpenSIUC (Southern Illinois University Carbondale)” Calotropis gigantea and Tridax procumbens extracts reduce inflammation more effectively than low-dose Ibuprofen.