research Spotlight Commentary: Importance of dose redefining in the process of drug repurposing
Redefining drug dosages is crucial when repurposing them for new uses.
Search
for
Sort by
Research
30 / 1000+ resultsresearch There Is a Positive Dose-Dependent Association between Low-Dose Oral Minoxidil and Its Efficacy for Androgenetic Alopecia: Findings from a Systematic Review with Meta-Regression Analyses
Low-dose oral minoxidil effectively promotes hair growth but has associated risks.
research Autologous cell–based therapy for male and female pattern hair loss using dermal sheath cup cells: A randomized placebo-controlled double-blinded dose-finding clinical study
DSC cell injections significantly improved hair density and diameter, showing potential as a hair loss treatment.
research Dissecting cellulitis (Perifolliculitis Capitis Abscedens et Suffodiens): a comprehensive review focusing on new treatments and findings of the last decade with commentary comparing the therapies and causes of dissecting cellulitis to hidradenitis suppura
New treatments for Dissecting cellulitis show promise, but more research is needed to understand the disease and establish a standard treatment plan.
research Prostate Carcinoma, what would be the best to do ?
Correct testosterone levels for age to treat prostate cancer, using low dose treatments as necessary.
research Clinical and genetic findings in a Chinese family with VDR-associated hereditary vitamin D-resistant rickets
A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.
research Problems Associated with the Recognition and Confirmation of Low-Dose Endocrine Toxicities
Confirming low-dose endocrine toxicities is difficult and requires more research.
research Dose-Response Relationship of Therapeutic Oxygen: More Is Not Necessarily Better and May Be Inferior to No Supplemental Oxygen – Part 2: Implications and Consequences
More oxygen isn't always better and can sometimes be worse.
research Low-dose oral minoxidil for androgenetic alopecia is not associated with significant changes in alcohol consumption: a retrospective study of 21,971 patients
Low-dose oral minoxidil does not significantly change alcohol consumption.
research 503 Use of low-dose spironolactone in female pattern hair loss in a specialty alopecia clinic
Low-dose spironolactone effectively treats female pattern hair loss with mild side effects.
research High‐dose pulsed corticosteroid therapy combined with methotrexate for severe alopecia areata of childhood
High-dose corticosteroids and methotrexate had a modest effect on severe childhood alopecia, but side effects and relapse were concerns.
research A Bio‐Functional Wnt3a Gradient Microarray for Cell Niche Studies
The study created a tool that mimics natural cell signals, which increased cell growth and could help with hair regeneration research.
research Short‐Term, Low‐Dose Spironolactone for Treatment of Hyperandrogenic Symptoms of Polycystic Ovary Syndrome—A Systematic Review
Spironolactone and metformin work similarly for PCOS symptoms, but more research is needed.
research Pooled safety and tolerability data from four placebo-controlled teriflunomide studies and extensions
Teriflunomide is safe and tolerable for treating relapsing-remitting multiple sclerosis, with manageable side effects.
research Selective delivery of adapalene to the human hair follicle under finite dose conditions using polymeric micelle nanocarriers
Polymeric micelle nanocarriers deliver adapalene more effectively to hair follicles than commercial products.
research Long-Term Efficacy of Ritlecitinib up to Month 24 From the ALLEGRO Phase 2b/3 and Long-Term Phase 3 Clinical Studies in Alopecia Areata
Ritlecitinib is effective for long-term treatment of severe alopecia areata.
research Platelet‐rich plasma with low dose oral minoxidil (1.25mg versus 2.5mg) along with trichoscopic pre‐ and post‐treatment evaluation
Combining platelet-rich plasma therapy with low dose oral minoxidil improved hair growth in men with hair loss, with slightly higher satisfaction at the higher minoxidil dose.
research Comparative efficacy of oral dutasteride and low-, medium-, and high-dose oral minoxidil: a six-month prospective trichoscopic and clinical study
Oral minoxidil improved hair loss more than oral dutasteride.
research Поняття міжкультурної комунікації та порівняльна характеристика німецької та української культур (на матеріалі німецької мови)
Low-dose effects in rodent studies are hard to confirm due to confounding factors and control group variability.
research Evaluation of the Safety and Effectiveness of Oral Minoxidil in Children: A Systematic Review
Low-dose oral minoxidil is safe for treating children's hair disorders.
research Topical minoxidil effectiveness in enhancing facial aesthetics: A systematic review and meta-analysis
Low-dose minoxidil effectively enhances facial hair with minimal side effects.
research Therapies
The document concludes that low-dose acne treatment is most suitable for moderate acne, with high patient satisfaction and low relapse rates.
research Keloid Formation and Any Skin Complications in Patients Treated With Isotretinoin and Undergone Any Skin‐Related Procedures
It's generally safe to have most skin procedures after isotretinoin, but avoid aggressive treatments and use a lower dose.
research Comparative Efficacy and Safety of Janus Kinase Inhibitors Used in Alopecia Areata: A Systematic Review and Meta-analysis
Baricitinib and deuruxolitinib are effective for treating alopecia areata, but their efficacy depends on the dose.
research Primary Generalized Glucocorticoid Resistance or Chrousos Syndrome: Allostasis Through a Mutated Glucocorticoid Receptor
Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.
research 131 Mutational landscape of extramammary Paget disease
The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.
research Hair
Alopecia areata causes significant emotional and social challenges, especially with more hair loss.
research An enzyme-linked immunosorbent assay for detection of botulinum toxin antibodies
Botox is effective for urinary incontinence, chronic migraines, and male pattern hair loss, and a new test for Botox antibodies is more humane.
research Highlights from the Literature
Apoptosis, not oxidative stress, is linked to aging in mice with mtDNA mutations.
research IN OTHER JOURNALS
Cellulite may be linked to low adiponectin, isotretinoin with UVB can treat psoriasis effectively, permanent alopecia post-chemotherapy resembles a unique hair loss, deodorants may cause fragrance allergies, desmoplastic melanoma is becoming more common, and intensive UVB treatment can give long-term psoriasis remission.