research Exosomes facilitate mRNA and siRNA delivery using cationic liposomes 2X3-DOPE to rat heart mesenchymal cells in vitro
Modified liposomes with exosomes effectively deliver RNA to stem cells.
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research Characterisation of Myotonic Dystrophy type I cell models and drug evaluation by a cell- based quantification platform.
Antisense oligonucleotides show promise for treating Myotonic Dystrophy type I.
research Skin Regeneration
New materials and methods could improve skin healing and reduce scarring.
research Transcription factor FOXC1 positively regulates SFRP1 expression in androgenetic alopecia
FOXC1 boosts SFRP1 in hair loss, suggesting new treatments.
research Understanding the functional contribution of dermal stem cells to hair follicle regeneration and skin wound healing
Dermal stem cells help regenerate hair follicles and heal skin wounds.
research Potential of nano-phytochemicals in cervical cancer therapy
Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.
research Surface modification and endothelialization of biomaterials as potential scaffolds for vascular tissue engineering applications
Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.
research What’s Sex Got to Do With COVID-19? Gender-Based Differences in the Host Immune Response to Coronaviruses
Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.
research KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype
Removing both KLK5 and KLK7 proteins can prevent death and skin issues in Netherton syndrome.
research Foxp3 Post-translational Modifications and Treg Suppressive Activity
Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.
research Beta-caryophyllene enhances wound healing through multiple routes
Beta-caryophyllene helps improve wound healing in mice, especially in females.
research Toll-Like Receptor Function in Acute Wounds
Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.
research JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin
JunB is crucial for maintaining healthy skin and hair follicles.
research Wnt/β-catenin signaling pathway activates melanocyte stem cells in vitro and in vivo
The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
research A wearable and stretchable dual-wavelength LED device for home care of chronic infected wounds
A new wearable LED device helps heal chronic infected wounds at home.
research Human genetic basis of coronavirus disease 2019
Genetic differences affect COVID-19 severity and treatment development.
research Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype
Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
research Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis
Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.
research Potential Use of Spin Traps to Control ROS in Antipollution Cosmetics—A Review
Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.
research Stem cells tightly regulate dead cell clearance to maintain tissue fitness
Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.
research RSL4 regulatory network acts as an early driver of root hair growth at low temperature in Arabidopsis thaliana
A gene network led by RSL4 is crucial for early root hair growth in response to cold in Arabidopsis thaliana.
research The development of an in vitro human hair follicle organoid with a complexity similar to that in vivo
Scientists created a lab-grown hair follicle model that behaves like real hair and could improve hair loss treatment research.
research COVID-19: How Effective Are the Repurposed Drugs and Novel Agents in Treating the Infection?
Vaccination is the most effective way to reduce COVID-19 transmission.
research NEW CHALLENGE TO CANCER AND LONGEVITY
A group has developed therapies that show promise for treating cancer and various other conditions.
research An Investigation of Keratin 15 Function by Small Interfering Ribonucleic Acid Technology
Keratin 15 affects cell behavior and characteristics in skin cells.
research Hodgkin′s lymphoma presenting as alopecia
Hodgkin's lymphoma can show up as hair loss.
research Antihelminthic Drugs
Antihelminthic drugs treat worm infections but face challenges like low treatment coverage and potential drug resistance, with various side effects reported for different drugs.
research Роль внеклеточных нуклеиновых кислот в процессах регенерации
Extracellular nucleic acids help start inflammation needed for tissue repair, but must be properly regulated.
research Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice
Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.
research Nanozymes expanding the boundaries of biocatalysis
Nanozymes greatly improve biocatalysis by being stable, efficient, and versatile.