October 2010 in “Journal of Men's Health” Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
April 2017 in “Actas urológicas españolas” 5-alpha reductase inhibitors increase the risk of sexual dysfunction in patients treating enlarged prostate but not in those treating hair loss.
July 2023 in “Zenodo (CERN European Organization for Nuclear Research)” Trazodone and chlorpromazine may help treat sexual dysfunction caused by finasteride and SSRIs.
December 2010 in “Actas Urológicas Españolas” Taking dutasteride for one month before prostate surgery can reduce bleeding.
20 citations
,
October 2018 in “Clinical Drug Investigation” Dutasteride does not impair mental function in elderly men with enlarged prostate.
1 citations
,
October 2023 in “Chest” Minoxidil can cause fluid buildup around the heart, so patients using it should be watched for this side effect.
34 citations
,
February 1992 in “Naunyn-schmiedebergs Archives of Pharmacology” Tedisamil and glibenclamide affect cromakalim and minoxidil sulphate differently in rat aorta.
Dutasteride is more effective than finasteride for treating BPH without extra safety risks.
September 2018 in “Translational Andrology and Urology” August 2022 in “Journal of The American Academy of Dermatology” A 5-mg dose of oral minoxidil slightly lowers blood pressure temporarily, especially in those with higher initial blood pressure.
11 citations
,
March 2007 in “Journal of Hypertension” Minoxidil effectively lowers blood pressure in resistant cases, but needs beta-blocker and diuretic support.
April 2017 in “The Journal of urology/The journal of urology” SHH protein helps nerve regeneration in hypertensive rats.
Tamsulosin and finasteride together effectively slow down and prevent BPH progression.
6 citations
,
January 1977 in “PubMed” Minoxidil effectively lowers severe high blood pressure long-term but isn't for routine use.
January 2014 in “Hebei yixue” Combining tamsulosin and finasteride effectively improves urinary symptoms in elderly BPH patients.
1 citations
,
March 2023 in “Journal of the American College of Cardiology” January 2004 in “Indian Journal of Nephrology” 14 citations
,
June 2014 in “World Journal of Urology” The herbal combination of saw palmetto and stinging nettle reduces nighttime urination in men with urinary issues.
36 citations
,
June 2014 in “International Journal of Dermatology” Dutasteride helps hair growth in those unresponsive to finasteride, but may cause more sexual dysfunction.
3 citations
,
January 2015 in “Journal of drug assessment” Taking five small dutasteride capsules is the same as taking one larger capsule.
January 2018 in “Surgical and Cosmetic Dermatology” Finasteride and dutasteride are effective for male hair loss and enlarged prostate but may cause reversible sexual side effects.
1 citations
,
July 2008 in “PubMed” 47 citations
,
January 2003 in “Current opinion in urology” A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.
45 citations
,
January 1981 in “Annals of Internal Medicine” Minoxidil controls blood pressure effectively, but may cause side effects like hypertrichosis.
September 2025 in “Reactions Weekly” May 2024 in “News Digital Object Group” 
July 2018 in “Reactions Weekly” Lower finasteride doses had more side effects; dutasteride caused back pain; more research needed on post-finasteride syndrome.
18 citations
,
January 1976 in “Clinical Science” Minoxidil effectively lowers severe high blood pressure but may cause side effects like increased hair growth.
November 1999 in “Reactions Weekly” 58 citations
,
March 2006 in “Current topics in medicinal chemistry” Dutasteride effectively treats benign prostatic hyperplasia and may reduce prostate cancer risk.