April 2016 in “Journal of Investigative Dermatology” Double-stranded RNA activates a pathway that causes a skin protein to be expressed in the wrong place.
April 2016 in “Journal of Investigative Dermatology” Blocking Prostaglandin D₂ (PGD₂) could help treat hair loss.
April 2016 in “Journal of Investigative Dermatology” Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.
April 2016 in “Journal of Investigative Dermatology” Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.
20 citations
,
January 2015 in “Current problems in dermatology” Hair gets thinner, grayer, and changes texture with age due to genetics, environment, and cellular changes, affecting the growth cycle.
1 citations
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June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.
No single biomarker is reliable enough for diagnosing and assessing SLE.
57 citations
,
February 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
38 citations
,
June 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” Peptide hydrogel scaffolds help grow new hair follicles using stem cells.
13 citations
,
July 2022 in “Frontiers in cell and developmental biology” Tiny natural vesicles from cells might help treat hair loss.
11 citations
,
September 2014 in “International Journal of Molecular Sciences” Mycophenolate helps reverse hair loss effects caused by IFN-γ by activating a key hair growth pathway.
27 citations
,
September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.
8 citations
,
May 2021 in “Bioengineering & translational medicine” Hair growth environment recreated with challenges; stem cells make successful skin organoids.
223 citations
,
January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
83 citations
,
January 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
56 citations
,
March 2015 in “Cell death and differentiation” Older skin has higher cancer risk due to inflammation and stem cell issues.
51 citations
,
September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
43 citations
,
January 2012 in “Biological Research” The origins of many adult skin stem cells are still mostly unknown.
18 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
15 citations
,
January 2020 in “ACS Applied Materials & Interfaces” Nanofiber structure helps regenerate hair follicles.
14 citations
,
March 2020 in “Cold Spring Harbor Perspectives in Biology” Mouse spermatogenesis shows that stem cells can behave flexibly and move widely in open environments.
13 citations
,
May 2022 in “Cell discovery” The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
5 citations
,
October 2024 in “International Journal of Biological Sciences” A peptide from hair follicle stem cells can boost hair growth.
November 2023 in “npj regenerative medicine” Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
989 citations
,
August 2007 in “The Lancet” PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.
336 citations
,
August 2015 in “European Journal of Epidemiology” The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
301 citations
,
February 2019 in “Nature Communications” The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.
144 citations
,
November 2020 in “Frontiers in immunology” Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.
135 citations
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December 2013 in “Seminars in Cell & Developmental Biology” Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.