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ASLAN004 was safe and well-tolerated, supporting further development for treating certain diseases.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

A new method accurately measures DHEAS in blood, improving on current tests.

Dihydroartemisinin helps reduce prostate enlargement in rats by stopping the growth of prostate cells.

Photoacoustic imaging can detect prostate brachytherapy seeds better with enhanced contrast methods, but depth limits remain.

Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.

CD34 is a marker for isolating stem-like cells in mouse hair follicles.

Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.

Human skin can produce steroids from cholesterol.

p2y5, now called LPA6, is a receptor important for human hair growth.

Plucking some hairs can trigger nearby unplucked hairs to grow back more due to a collective response.

Human hair is made up of different keratins, some strong and some weak, with specific types appearing at various stages of hair growth.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

Vitamin D receptor and hairless protein are essential for hair growth.

Drug repositioning offers a cost-effective, lower-risk way to treat diseases and pandemics like COVID-19.

Matriptase is crucial for skin, hair, and immune cell health, and its imbalance can lead to cancer.

Overexpressing follistatin in mice delays wound healing and reduces scar size.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

CD34 is crucial for skin tumor development in mice.

Trichohyalin is modified by enzymes to form strong structures in hair cells.

A reliable system was developed to distinguish hair growth stages, aiding in identifying hair growth promoters or inhibitors.

Dlx3 is essential for hair growth and regeneration.

GKLF/KLF4 and Sp1 control Keratin 19 gene activity, influencing cancer-related changes.

Surgical face-lifts are more effective, but fractional radiofrequency is a good, less invasive alternative for treating skin laxity.

Neuropeptides affect hair growth, with some speeding it up and others slowing it down.

Reduced matriptase activity causes skin and hair issues in both humans and mice.

Matriptase is crucial for skin barrier, hair growth, and may contribute to skin cancer.