research Next generation human skin constructs as advanced tools for drug development
Advanced human skin models improve drug development and could replace animal testing.
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research DRUG‐ASSOCIATED ALOPECIA
Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.
research Spironolactone in combination drug therapy for unresponsive hirsutism
Combination drug therapy is effective for hirsutism that doesn't improve with just one medication.
research 3D printed microneedles: revamping transdermal drug delivery systems
3D-printed microneedles improve drug delivery by being precise, cost-effective, and less invasive.
research Network-Based Drug Repositioning: Approaches, Resources, and Research Directions
The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.
research Therapeutic Applications of Nanoemulsion Based Drug Delivery Systems: A Review of Patents in Last Two Decades
Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.
research Methods for quantifying intrafollicular drug delivery: a critical appraisal
The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
research How drug repurposing can advance drug discovery: challenges and opportunities
Drug repurposing is a faster, cheaper way to develop new treatments using existing drugs.
research Exploring pericyte and cardiac stem cell secretome unveils new tactics for drug discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
research Drug reaction with eosinophilia and systemic symptoms and severe involvement of digestive tract: description of two cases
Severe digestive issues in DRESS need early endoscopy for better treatment.
research In vitro selective inhibition of human UDP-glucuronosyltransferase (UGT) 1A4 by finasteride, and prediction of in vivo drug–drug interactions
Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.
research Nanocarrier Systems for Transdermal Drug Delivery
Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
research Drug eruptions in dermatology
Skin reactions to drugs are common and can be deadly, usually requiring stopping the drug and may be better prevented with genetic testing in the future.
research Drug-induced postinfantile giant cell hepatitis
Certain liver diseases respond well to specific treatments and have varying risks for liver cancer.
research An overview of management of drug-induced hair and nail disorders
Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.
research Maintenance of optimised hair growth from viable terminal scalp hair follicles at baseline with oral finasteride in male pattern hair loss and first evidence of a “drug dependency” and a post-finasteride “rebound effect”.
Finasteride helps hair growth but stopping it causes faster hair loss.
research HHV-6A and HHV-6B in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms
The document concludes that reactivation of herpesviruses, especially HHV-6, is linked to severe symptoms and complications in drug-induced hypersensitivity syndrome.
research Percutaneous Drug Delivery to the Hair Follicle
Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
research Real-world pharmacovigilance insights into drug-induced risk of alopecia
64 drugs can cause hair loss, needing better monitoring and updated labels.
research Drug Armamentarium for alopecia areata
No cure exists for alopecia areata, and treatments are personalized.
research Drug Treatment of Acute Leukaemia Current Status
Treatments for acute leukaemia lead to high remission rates, but relapses occur, requiring ongoing advancements in care.
research The Use/Abuse of Oral Contraceptive Pills Among Males: A Mixed-Method Explanatory Sequential Study Over Jordanian Community Pharmacists
Many males in Jordan misuse oral contraceptive pills for hair growth, muscle gain, and acne treatment.
research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
research Lecithin organogels as a potential phospholipid-structured system for topical drug delivery: A review
Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.
research Transfollicular drug delivery—Is it a reality?
Hair follicles may soon be used more for targeted and systemic drug delivery.
research Identification of drug-specific public TCR driving severe cutaneous adverse reactions
Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
research Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro
Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.
research The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results
Both mouse and rat models are effective for testing alopecia areata treatments.
research Hyperbranched glycerol-based core-amphiphilic branched shell nanotransporters for dermal drug delivery
New nanocarriers improve skin drug delivery with low toxicity at certain concentrations.
research Transfollicular drug delivery: current perspectives
Transfollicular drug delivery is promising but needs more research to improve and understand it better.