1 citations
,
January 2017 in “Springer eBooks” Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.
54 citations
,
October 2002 in “Journal of controlled release” Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.
January 2024 in “Research Portal Denmark” Artificial hair fibers improve drug delivery accuracy through skin models.
47 citations
,
June 1996 in “International Journal of Legal Medicine” Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.
29 citations
,
May 2007 in “International journal of pharmaceutics” Different compounds move through artificial sebum at different rates, which can help choose the best ones for targeting hair follicles.
1 citations
,
July 2005 in “CRC Press eBooks” Topical drugs can target hair follicles to treat skin conditions more effectively.
95 citations
,
July 2015 in “European journal of pharmaceutics and biopharmaceutics” Lipid nanoparticles can help deliver drugs through hair follicles but struggle to penetrate deeper skin layers.
55 citations
,
September 2017 in “Expert Opinion on Drug Discovery” Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.
60 citations
,
October 2020 in “Journal of Controlled Release” Curcumin nanocrystals in simple gels effectively penetrate hair follicles, but humectants can reduce this efficacy.
64 citations
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April 2005 in “Journal of Investigative Dermatology” Topical oligonucleotide therapy targets hair follicles effectively.
1 citations
,
July 2005 in “Informa Healthcare eBooks” Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
7 citations
,
February 2018 in “International Journal of Pharmaceutics” Researchers developed a method to measure drugs in hair follicles and found that both water-loving and fat-loving drugs can be detected after being applied to the skin.
34 citations
,
July 2010 in “Expert Opinion on Drug Delivery” The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
151 citations
,
November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
67 citations
,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
34 citations
,
October 2014 in “European journal of pharmaceutics and biopharmaceutics” The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.
25 citations
,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” New methods like nanoparticles and microneedles show promise for better skin drug delivery, especially for hair disorders.
13 citations
,
October 2012 in “InTech eBooks” Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
8 citations
,
December 2021 in “Military Medical Science Letters” Nanoemulgel is a promising method for delivering drugs, especially for those that don't dissolve well in water.
1 citations
,
January 2001 in “Journal of Toxicology-cutaneous and Ocular Toxicology” Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.
May 2023 in “Current Medicinal Chemistry” Microneedle patches improve drug delivery for skin treatments and cosmetic enhancements.
151 citations
,
July 2011 in “Archives of Dermatological Research” Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
141 citations
,
November 2005 in “International journal of pharmaceutics” Hair follicles may soon be used more for targeted and systemic drug delivery.
33 citations
,
June 2007 in “International Journal of Pharmaceutics” The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.
19 citations
,
October 2020 in “Biomedical Microdevices” Derma rollers show promise for skin improvement and drug delivery, but more research is needed on their safety and effectiveness.
10 citations
,
May 2016 in “Polymer” New nanocarriers improve skin drug delivery with low toxicity at certain concentrations.
10 citations
,
April 2016 in “Research and reports in transdermal drug delivery” Transfollicular drug delivery is promising but needs more research to improve and understand it better.
5 citations
,
June 2022 in “Frontiers in veterinary science” Improving how drugs are absorbed through the skin could better treat mange in wombats.
1 citations
,
November 2024 in “Pharmaceutical Sciences” Deformable vesicular carriers improve drug delivery for skin conditions and systemic treatments.
March 2024 in “Bioimpacts” 400 nm particles penetrate hair follicles best, but mouse models aren't fully reliable for human studies.