96 citations
,
September 2021 in “International Journal of Molecular Sciences” Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
95 citations
,
July 2015 in “European journal of pharmaceutics and biopharmaceutics” Lipid nanoparticles can help deliver drugs through hair follicles but struggle to penetrate deeper skin layers.
84 citations
,
March 2004 in “Veterinary Dermatology” Cyclosporin is effective in treating dog skin diseases and has fewer side effects compared to other treatments.
82 citations
,
January 1997 in “Forensic science international” Drugs can be incorporated into hair based on their chemical properties and hair pigmentation.
76 citations
,
January 2022 in “Journal of Tissue Engineering” Microneedle patches could replace injections but need more development for better use in medicine.
70 citations
,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
69 citations
,
June 2017 in “Experimental Biology and Medicine” Advanced human skin models improve drug development and could replace animal testing.
68 citations
,
February 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” Keratin films from human hair can potentially replace human nail plates for drug testing.
67 citations
,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
65 citations
,
May 2001 in “Journal of Analytical Toxicology” Basic drugs like amphetamine are absorbed more in darker hair than lighter hair.
63 citations
,
March 1995 in “International Journal of Dermatology” Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.
56 citations
,
January 2023 in “Genes & Diseases” Repurposing existing drugs and using micronutrients may effectively target cancer stem cells and improve cancer treatment.
56 citations
,
June 1970 in “The BMJ” Drug addicts often have scars, skin color changes, blocked veins, and bruising, with severe ulcers from barbiturate injections.
55 citations
,
March 2018 in “Journal of pharmacy & pharmaceutical sciences” Microneedles help improve drug delivery through the skin and are used in medicine and beauty treatments.
52 citations
,
October 2016 in “Clinics in Dermatology” Some medications can cause acne, and stopping these drugs is the main treatment.
51 citations
,
October 2024 in “Pharmaceutics” Improving drug delivery through the skin requires understanding skin and using enhancers.
49 citations
,
December 2018 in “JAAD case reports” Dupilumab may cause significant hair loss, which can reverse after stopping the drug.
48 citations
,
July 2023 in “Biomedicines” Hydrogel-forming microneedles are promising for safe, efficient, and controlled drug delivery through the skin.
47 citations
,
June 1996 in “International Journal of Legal Medicine” Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.
42 citations
,
June 2021 in “Pharmaceutics” 3D printing can make microneedles for drug delivery faster and cheaper.
42 citations
,
January 2018 in “Expert review of precision medicine and drug development” Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.
41 citations
,
August 2024 in “Drug Delivery and Translational Research” 3D-printed microneedles improve drug delivery by being precise, cost-effective, and less invasive.
40 citations
,
August 2006 in “Current Drug Safety” Some drugs can cause hair loss, excessive growth, or color changes, often reversible but sometimes permanent.
39 citations
,
April 2020 in “IntechOpen eBooks” Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
39 citations
,
December 2018 in “Methods in molecular biology” The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.
39 citations
,
January 2013 in “Skin pharmacology and physiology” Nanoparticles show promise for drug delivery through hair follicles but not through healthy skin.
39 citations
,
April 2012 in “Journal of controlled release” New method uses hair follicles to deliver drugs deep into the skin.
39 citations
,
April 2011 in “Recent Patents on Drug Delivery & Formulation” Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.
36 citations
,
November 2016 in “European journal of dermatology/EJD. European journal of dermatology” Some medications can cause rare hair color changes, and reporting these side effects is important for patient quality of life.
34 citations
,
October 2014 in “European journal of pharmaceutics and biopharmaceutics” The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.