Reviewers criticized the study for assuming drugs with similar side-effects work the same way and questioned the validity of its findings due to potential biases and data quality issues.
April 2002 in “Annals of Internal Medicine” Isotretinoin may increase the risk of high triglycerides and metabolic syndrome, especially in those genetically prone.
May 2024 in “Indian Journal of Pharmacology” An 11-year-old girl with alopecia totalis experienced complete hair loss on her scalp and was initially treated with topical minoxidil, azathioprine, and dexamethasone. The treatment led to hair growth on her forehead but not on her scalp, and azathioprine caused transaminitis. After discontinuing azathioprine and minoxidil, and starting tofacitinib, the girl's scalp hair regrew, and forehead hypertrichosis resolved. The case highlights the importance of proper minoxidil application to avoid hypertrichosis and demonstrates the effectiveness of tofacitinib in treating alopecia areata. Proper patient counseling on minoxidil use is crucial to prevent side effects.
November 2022 in “International Journal of Trichology” Finasteride can cause rare but serious skin rashes.
The model predicts minoxidil's effectiveness and side effects better than traditional methods.
Reviewers criticized the study's methods and suggested focusing on drug mechanisms instead of repositioning due to social media data quality concerns.
Reviewers suggested the study on finding new drug uses through social media side-effects needs better methods and clearer limitations.
The peer review highlighted the need for clearer data handling, questioned the study's validity, and recognized improvements from the original version.
Reviewers criticized the study for its assumptions, social media data collection issues, and lack of comparison to existing methods.
The study improved and was accepted despite initial concerns about data clarity, methodology, and potential overfitting.
2 citations
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June 2009 in “PubMed” 
January 2016 in “Vojnosanitetski Pregled” Some treatments for inflammatory bowel disease can cause skin problems like rashes and melanoma.
16 citations
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July 1996 in “Dermatologic Clinics” Some psychiatric drugs can cause skin problems, but serious reactions are rare.
1 citations
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July 2006 in “American Journal of Psychiatry” Lamotrigine can cause hair loss.
February 2026 in “Cureus” Recognizing and managing skin side effects from chemotherapy improves patient quality of life and treatment success.
September 2025 in “Journal of Psychiatry Spectrum” Mirtazapine can cause male breast enlargement.
18 citations
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May 2013 in “Cutaneous and Ocular Toxicology” The cancer drugs bortezomib and lenalidomide cause skin side effects in many patients.
February 2026 in “Pharmaceuticals” KRDQN effectively predicts adverse drug reactions with high accuracy and clear explanations.
122 citations
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March 2013 in “Expert opinion on drug delivery” Optimizing drug delivery to hair follicles is crucial for effective treatment.
7 citations
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March 2018 in “Dermatology and therapy” Finasteride is considered the best treatment for hair loss, despite side effects.
April 2025 in “Archives of Dermatological Research” Microneedling therapy leads to better treatment adherence than drug therapy for hair loss.
January 2026 in “Clinical & Translational Oncology” Early intervention and tailored management are crucial for skin side effects in cancer treatments.
61 citations
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April 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.
1 citations
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January 2024 in “Revista CUIDARTE” Patients prefer non-drug methods like massage and music to manage chemotherapy side effects, but standardization is needed.
2 citations
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March 2015 in “Clinical and Experimental Dermatology” Azathioprine can cause unusual hair loss, which may reverse after stopping the drug.
61 citations
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March 1990 in “Clinical pharmacology and therapeutics/Clinical pharmacology & therapeutics” Albendazole treatment for echinococcosis can cause serious side effects and requires close monitoring.
January 2015 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” A 5-year-old girl with McCune-Albright syndrome grew abnormal hair due to the drug tamoxifen.
June 2011 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Finasteride, a hair loss drug, can cause long-lasting sexual side effects like low libido and erectile dysfunction.
October 2021 in “International Journal of Andrology” Finasteride, a hair loss drug, has unaddressed sexual side effects due to the manufacturer's inadequate safety measures and lack of additional studies.
January 2020 in “Archives of urology” Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.