research Selective non-steroidal inhibitors of 5α-reductase type 1
Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.
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research Endophytes in Southeast Asia and Japan: their taxonomic diversity and potential applications
Endophytes from Southeast Asia and Japan can produce useful substances like enzymes and antibiotics.
research Preparation and characterization of dutasteride-loaded nanostructured lipid carriers coated with stearic acid-chitosan oligomer for topical delivery
The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.
research Human type 3 5α-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride
Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.
research Comprehensive analysis of circRNAs from cashmere goat skin by next generation RNA sequencing (RNA-seq)
Four circRNAs were found to be significantly different in cashmere goat skin, affecting cashmere fineness.
research Stem cell factor/c-Kit signalling in normal and androgenetic alopecia hair follicles
SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.
research Side effects of common acne treatments
Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.
research Redefining hormone resistance in prostate cancer
The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
research How to Speak Postmodern: Medicine, Illness, and Cultural Change
The document suggests medicine should integrate biological and cultural factors and focus on holistic, equitable care.
research Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation
Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
research Hyperplasia of Hair Follicles and Other Adnexal Structures in Cutaneous Lymphoproliferative Disorders
Hair follicle hyperplasia is common in both benign and malignant skin lymphoproliferative disorders, with a proposed new term "pseudolymphomatous adnexitis."
research Surgical approach to adolescent obesity
Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.
research Hair problems in women
Hair problems are common and distressing for women, but increasing knowledge of treatments offers hope.
research Macrophages Promote Wound-Induced Hair Follicle Regeneration in a CX3CR1- and TGF-β1–Dependent Manner
Macrophages help hair growth after injury through CX3CR1 and TGF-β1.
research Skin and hair: models for exploring organ regeneration
Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
research Alteration of Ethanol Drinking in Mice via Modulation of the GABAA Receptor with Ganaxolone, Finasteride, and Gaboxadol
Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.
research In Vitro and In Vivo Skin Distribution of 5α-Reductase Inhibitors Loaded Into Liquid Crystalline Nanoparticles
Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.
research Male Breast Cancer and 5α-Reductase Inhibitors Finasteride and Dutasteride
Using finasteride or dutasteride does not increase the risk of male breast cancer.
research Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro
Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
research Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix
CIP/KIP proteins help stop cell division and support hair growth.
research Experimental and thermodynamic analyses of supercritical CO2-Solubility of minoxidil as an antihypertensive drug
Minoxidil dissolves better in propylene glycol + water than in supercritical CO2.
research Cystathionine β‐synthase‐deficient mice thrive on a low‐methionine diet
Mice with CBS deficiency are healthier on a low-methionine diet.
research Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity
Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
research Hormonal prevention of prostate cancer
Suppressing certain hormones might help prevent prostate cancer.
research Association of alopecia areata with atopic dermatitis and chronic spontaneous urticaria
People with alopecia areata often have higher rates of allergies and autoimmune diseases.
research Platelet-Rich Plasma for the Aesthetic Surgeon
Platelet-Rich Plasma (PRP) shows promise for hair growth and skin improvement in aesthetic surgery.
research Post-finasteride syndrome: An emerging clinical problem
Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.
research An Integrated Analysis of Cashmere Fineness lncRNAs in Cashmere Goats
lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.
research Regenerative medicine meets mathematical modelling: developing symbiotic relationships
Mathematical modeling can improve regenerative medicine by predicting biological processes and optimizing therapy development.
research Clinicopathologic Comparison of Radiofrequency Versus Scalpel Incision for Upper Blepharoplasty
Radiofrequency and scalpel incisions have similar clinical outcomes for upper eyelid surgery.