144 citations
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September 2006 in “Clinics in Dermatology” Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
129 citations
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October 2007 in “The New England Journal of Medicine” Over one-third of women experience hair loss, with female-pattern hair loss being most common, and treatments include minoxidil and possibly hair transplantation.
119 citations
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November 2014 in “Trends in Cell Biology” Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.
118 citations
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October 2013 in “Trends in Genetics” The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
77 citations
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May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
73 citations
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July 2013 in “The Journal of Sexual Medicine” Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.
72 citations
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January 2001 in “Drugs” Minoxidil and finasteride treat hair loss; more research needed for other options.
71 citations
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November 2012 in “Expert Opinion on Drug Safety” 5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.
68 citations
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May 2021 in “Endocrine” People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.
61 citations
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April 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.
55 citations
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October 2019 in “Dermatology and therapy” Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.
52 citations
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February 2006 in “Current pharmaceutical design” 5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.
43 citations
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August 2016 in “Scientific Reports” Cinnamomi cortex may help treat prostate enlargement by reducing related proteins.
42 citations
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November 2002 in “The American journal of pathology” Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.
40 citations
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April 2018 in “Endocrine” PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.
37 citations
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June 2011 in “Journal of Cellular Biochemistry” Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
37 citations
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April 2008 in “The Cochrane library” 5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.
36 citations
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June 2014 in “International Journal of Dermatology” Dutasteride helps hair growth in those unresponsive to finasteride, but may cause more sexual dysfunction.
34 citations
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June 2011 in “Alcoholism: Clinical and Experimental Research” Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.
29 citations
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November 2012 in “Journal of The European Academy of Dermatology and Venereology” Use 5% minoxidil or oral finasteride for mild-to-moderate hair loss, combine with hair transplant for severe cases.
28 citations
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November 2013 in “The FASEB journal” Mice with CBS deficiency are healthier on a low-methionine diet.
23 citations
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October 2018 in “Expert Opinion on Drug Safety” Consider benefits and risks of new alopecia treatments for safety.
22 citations
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August 2014 in “Clinical endocrinology” Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.
22 citations
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October 2012 in “Journal of Investigative Dermatology” Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.
21 citations
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April 2016 in “Journal of Dermatological Treatment” Finasteride may cause mental and sexual side effects, with hand preference and sexual orientation possibly affecting severity.
21 citations
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March 2006 in “Seminars in Cutaneous Medicine and Surgery” Most hair loss disorders can be accurately diagnosed and treated in an outpatient setting.
21 citations
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July 1988 in “Clinics in dermatology” Good haircare and communication with doctors are key for managing hair loss.
20 citations
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August 2019 in “Expert Opinion on Drug Safety” Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.
20 citations
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February 1991 in “The Journal of Dermatologic Surgery and Oncology” Scalp flaps are used for reconstruction, considering factors like inelasticity, hair growth, and blood supply, with techniques adapting to age-related changes in vascularity.
19 citations
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April 2014 in “Hormones” Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.