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research Polymorphisms of the genes ABCG2, SLC22A12 and XDH and their relation with hyperuricemia and hypercholesterolemia in Mexican young adults

5 citations , March 2021 in “F1000Research”

A specific gene variation increases the risk of high uric acid and cholesterol in young Mexican males.

Preliminary Pharmacokinetics and Metabolism of Novel Non-Steroidal Antiandrogens in the Rat: Relation of Their Systemic Activity to the Formation of a Common Metabolite

research Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: Relation of their systemic activity to the formation of a common metabolite

16 citations , October 1994 in “The Journal of Steroid Biochemistry and Molecular Biology”

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

First Case of V281+I172N/V281L CYP21A2 Genotype Associated with Congenital Adrenal Hyperplasia: A Case Report from Southern Italy

research First case of V281+I172N/V281L CYP21A2 genotype associated with congenital adrenal hyperplasia form. A case report from South Italy

October 2007 in “Clinical Biochemistry”

New genotype linked to non-classical congenital adrenal hyperplasia found in Italian siblings.

research Bone morphogenetic proteins 4 and 2/7 induce osteogenic differentiation of mouse skin derived fibroblast and dermal papilla cells

28 citations , November 2013 in “Cell and Tissue Research”

research Cutaneous hydroxystereoid dehydrogenases and rat-hair-cycle

2 citations , January 1975 in “Archives of Dermatological Research”

Certain enzymes react strongly with some hormones in rat skin during hair growth, mainly in sebaceous glands and hair sheaths.

research 549 Temporary cell cycle arrest in human scalp hair follicles and their epithelial stem cells by ALRN-6924: A novel strategy to selectively protect p53-wildtype cells against paclitaxel-induced alopecia

1 citations , November 2022 in “Journal of Investigative Dermatology”

ALRN-6924 may prevent hair loss caused by chemotherapy.

Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle

research Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle

32 citations , February 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.

research De novo follicular regeneration of the skin by wingless int 3 and bone morphogenetic protein 2 genes introduced into dermal fibroblasts and fibroblast growth factor‐2 protein

4 citations , May 2009 in “Wound Repair and Regeneration”

Genetically modified cells can regenerate skin and hair in rats.

research Relative efficacy of minoxidil and 5-alpha-reductase inhibitors in the treatment of male androgenetic alopecia: protocol for a network meta-analysis study

1 citations , May 2021

research Gender-Difference in Hair Length as Revealed by Crispr-Based Production of Long-Haired Mice with Dysfunctional FGF5 Mutations

6 citations , October 2022 in “International Journal of Molecular Sciences”

Male mice with FGF5 mutations grow longer hair than females.

research A pilot study evaluating dosing tolerability of 17α-estradiol in male common marmosets (Callithrix jacchus)

1 citations , August 2024 in “GeroScience”

research Treatment of Erythromelanosis Follicularis Faciei et Colli Using a Dual-Wavelength Laser System: A Split-Face Treatment

11 citations , June 2010 in “Dermatologic surgery”

The dual-wavelength laser system effectively reduces EFFC symptoms with minimal side effects.

research Genetic effects of vascular endothelial growth factor and its receptor 2 on feather maturity in three chicken breeds

1 citations , January 2019 in “British Poultry Science”

VEGF and VEGFR-2 genes influence feather maturity, and specific genetic markers can improve chicken breeding.

research Identifying causal genes in alopecia areata using integrative analysis of differential expression and Mendelian randomization

July 2024

Four genes are linked to alopecia areata, with two increasing risk and two offering protection.

research Progestogens with Antiandrogenic Properties

164 citations , January 2003 in “Drugs”

research A Neutralizing Prolactin Receptor Antibody Whose In Vivo Application Mimics the Phenotype of Female Prolactin Receptor-Deficient Mice

14 citations , August 2015 in “Endocrinology”

The antibody 005-C04 blocks prolactin receptors, causing reversible infertility, impaired lactation, and hair regrowth in female mice.

research Inhibiting the cytosolic function of CXXC5 accelerates diabetic wound healing by enhancing angiogenesis and skin repair

19 citations , August 2023 in “Experimental & Molecular Medicine”

Blocking CXXC5 speeds up diabetic wound healing by improving blood vessel growth and skin repair.

research Melanocytes from the outer root sheath of human hair and epidermal melanocytes display improved melanotic features in the niche provided by cGEL, oligomer-cross-linked gelatin-based hydrogel

7 citations , July 2016 in “Journal of Biomedical Materials Research Part A”

cGEL hydrogel improves melanin production in skin cells, making it a promising option for skin treatments.

research Association of prior 5-α-reductase inhibitor exposure with ICI benefit in metastatic RCC: Multicentre cohort with single-cell immune profiling.

March 2026 in “Journal of Clinical Oncology”

Using 5-α-reductase inhibitors before treatment improves outcomes for patients with metastatic renal cell carcinoma.

research The use of polyethylenimine–DNA to topically deliver hTERT to promote hair growth

17 citations , May 2011 in “Gene Therapy”

Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.

research Enrichment and Characterization of Human Dermal Stem/Progenitor Cells by Intracellular Granularity

10 citations , January 2013 in “Stem Cells and Development”

Scientists identified a unique type of human skin stem cell that could help with tissue repair.

research Effects of FGF5-mediated LncRNA on the skin fibroblast growth of Liaoning Cashmere goats

July 2023 in “Indian Journal of Animal Health”

FGF-5 promotes Cashmere goat hair growth by increasing keratin genes and reducing certain LncRNA and target genes.

research Transgenic mouse models support HCR as an effector gene in the PSORS1 locus

37 citations , June 2004 in “Human molecular genetics online/Human molecular genetics”

The HCR gene contributes to psoriasis risk.

research Development of an aequorin-based assay for the screening of corticotropin-releasing factor receptor antagonists

November 2015 in “Journal of the Korea Academia-Industrial cooperation Society”

The new assay can help develop products for hair re-growth.

Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase

research Synthesis and in vitro study of 17β-[N-ureylene-N,N′-disubstituted]-4-methyl-4-aza-5α-androstan-3-ones as selective inhibitors of type I 5α-reductase

5 citations , February 1997 in “Bioorganic & Medicinal Chemistry”

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Characterization of Myotonic Dystrophy Type I Cell Models and Drug Evaluation by a Cell-Based Quantification Platform

research Characterisation of Myotonic Dystrophy type I cell models and drug evaluation by a cell- based quantification platform.

November 2024 in “Communities in ADDI (University of the Basque Country)”

Antisense oligonucleotides show promise for treating Myotonic Dystrophy type I.

research 1358 PRC1 fine-tunes gene repression and activation to safeguard skin epithelium development and stem cell specification

1 citations , April 2018 in “Journal of Investigative Dermatology”

PRC1 is essential for proper skin development and stem cell formation by controlling gene activity.

research 022 Randomized, double-blind, placebo-controlled, single-centre, phase I safety study of intradermal injections of autologous fibroblasts isolated from the non-bulbar dermal sheath of the hair follicle to treat skin aging

September 2017 in “Journal of Investigative Dermatology”

RCS-01 is safe and may help rejuvenate aging skin.

research Vitamin E TPGS based transferosomes augmented TAT as a promising delivery system for improved transdermal delivery of raloxifene

30 citations , December 2019 in “PLoS ONE”

The new delivery system improved raloxifene's skin absorption and effectiveness against cancer cells.

research TERT/BMI1-transgenic human dermal papilla cells enhance murine hair follicle formation in vivo

1 citations , March 2022 in “Journal of Dermatological Science”

Adding TERT and BMI1 to certain skin cells can improve their ability to create hair follicles in mice.

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