297 citations
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January 2002 in “Development” Overexpression of ΔNLef1 in mouse skin leads to hair loss, cysts, and skin tumors.
September 2017 in “Journal of Investigative Dermatology” Hair follicle cells change their DNA packaging during growth cycles and when grown in the lab.
150 citations
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June 1999 in “Oncogene”
202 citations
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August 2017 in “Nature cell biology” Lactate production is important for activating hair growth stem cells.
13 citations
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July 2019 in “Journal of Dermatological Science” Increasing alkaline phosphatase in human skin cells helps to grow more hair.
Electrical stimulation with minoxidil boosts hair cell growth.
4 citations
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January 2013 in “Genetics and Molecular Research” VEGF and microvessel density are closely linked and peak during specific hair growth phases in cashmere goats.
Dermal papilla cells can help form hair-like structures in lab-grown skin cells.
18 citations
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April 2019 in “Archives of Dermatological Research” Lactoferrin helps mice grow hair by increasing cell growth and hair follicle development.
136 citations
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June 2006 in “Journal of Dermatological Science” PDGF isoforms can promote and sustain hair growth.
94 citations
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March 1996 in “Journal of Investigative Dermatology”
149 citations
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July 2017 in “PLoS Biology” Hair follicle patterns form through a mix of self-organization and signaling interactions.
1 citations
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June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” GTL1 is needed to control root hair growth and prevent problems when there are too many nutrients.
December 2012 in “Journal of dermatological science” Langerhans cells and melanocytes migrate to the skin and hair follicles during early human development.
17 citations
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June 1997 in “Baillière's clinical obstetrics and gynaecology” Scientists now better understand how human hair growth is controlled, including the roles of specific genes and proteins.
11 citations
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October 2017 in “Oncotarget” Gsdma3 affects hair growth by controlling Wnt5a, which influences hair cell development.
42 citations
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February 2017 in “Scientific Reports” Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.
287 citations
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March 1999 in “The Plant Journal” Microtubules help control the direction and stability of root hair growth in Arabidopsis thaliana.
421 citations
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September 2003 in “Development” Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.
July 2025 in “Journal of Investigative Dermatology” Secreted inhibitors of Wnt and IGF signaling control hair and tooth development, creating species-specific patterns.
Understanding hair follicle communication can help treat hair loss.
November 2025 in “Journal of Investigative Dermatology” NUL-5 may boost hair growth by improving hair follicle health and structure.
170 citations
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July 2012 in “Journal of Investigative Dermatology” Wnt ligands are crucial for hair growth and repair.
17 citations
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November 1967 in “American Journal of Anatomy” Hairless mice have longer hair follicles and abnormal structures during the catagen phase.
79 citations
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January 2002 in “Nucleic Acids Research” BMP-2 activates the Dlx3 gene in mouse skin cells, important for hair and skin development.
February 2023 in “International Journal of Molecular Sciences” Exosomes from skin cells can boost hair growth by stimulating a gene called LEF1.
92 citations
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February 2005 in “Endocrinology” Estrogen receptors affect hair growth, with ER beta slowing down the hair cycle changes caused by ER alpha.
28 citations
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May 2000 in “Proceedings of the National Academy of Sciences” The Walleye dermal sarcoma virus cyclin causes excessive skin cell growth in mice.
3 citations
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August 2012 in “Nature Cell Biology” Certain proteins help nerve cells branch, and other findings relate to cancer, stem cell behavior, and cell division.
3 citations
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September 2024 3DEEP reveals early hair follicle stem cell formation and niche establishment before hair bulb development.