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GlossaryDysplastic Nevi

unusual moles that may resemble melanoma but aren't cancerous

Dysplastic nevi, also known as atypical moles, are unusual-looking benign moles that may resemble melanoma but are not cancerous. They often have irregular borders, varied colors, and are larger than common moles. While they themselves are not harmful, having multiple dysplastic nevi can increase the risk of developing melanoma, so regular monitoring by a dermatologist is recommended.

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Skin Self-Photography for Dysplastic Nevus Monitoring Is Associated with a Decrease in the Number of Biopsies at Follow-Up: A Retrospective Analytical Study

research Skin self-photography for dysplastic nevus monitoring is associated with a decrease in the number of biopsies at follow-up: A retrospective analytical study

5 citations , September 2015 in “Journal of The American Academy of Dermatology”

Taking photos of your own skin can lead to fewer skin biopsies for mole monitoring.

research Becker's nevus associated with chromosomal mosaicism and congenital adrenal hyperplasia

32 citations , April 1994 in “Journal of the American Academy of Dermatology”

High androgen levels and genetic factors likely cause Becker's nevus and related symptoms.

research Topikal Retinoidler

March 2021

Tretinoin is used topically to treat acne, skin aging, and various skin conditions.

research Hair Loss in Children, Etiologies, and Treatment

May 2017 in “InTech eBooks”

Early treatment of children's hair loss, which can be caused by various factors, is important due to its emotional impact.

research Dysplastic nevi, cutaneous melanoma, and other skin neoplasms in patients with myotonic dystrophy type 1: A cross-sectional study

23 citations , January 2015 in “Journal of The American Academy of Dermatology”

People with myotonic dystrophy type 1 have a higher chance of getting skin tumors, including melanoma.

research PA15 Becker naevus syndrome associated with a mosaic pathogenic variant in ACTB

June 2023 in “British journal of dermatology/British journal of dermatology, Supplement”

A girl with Becker naevus syndrome has a genetic variant in the ACTB gene related to her symptoms.

research Ectodermal Dysplasia: Otolaryngologic Manifestations and Management

37 citations , June 2002 in “The Laryngoscope”

Ectodermal dysplasia causes various symptoms and early treatment is important for eye, dental, and skin issues.

research Porokeratotic Eccrine Duct and Hair Follicle Nevus (PEHFN) Associated with Keratitis-Ichthyosis-Deafness (KID) Syndrome

17 citations , September 2010 in “Pediatric dermatology”

A 15-year-old with KID syndrome developed a rare skin condition called PEHFN.

research WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation

96 citations , June 2017 in “Nature Communications”

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

research Histopathological and Ultrastructural Study of Ectodermal Dysplasia/Skin Fragility Syndrome

31 citations , August 2005 in “The American Journal of Dermatopathology”

The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.

Deficient Plakophilin-1 Expression Due to a Mutation in PKP1 Causes Ectodermal Dysplasia-Skin Fragility Syndrome in Chesapeake Bay Retriever Dogs

research Deficient Plakophilin-1 Expression Due to a Mutation in PKP1 Causes Ectodermal Dysplasia-Skin Fragility Syndrome in Chesapeake Bay Retriever Dogs

28 citations , February 2012 in “PLoS ONE”

A PKP1 gene mutation causes skin fragility and hair loss in Chesapeake Bay retriever puppies.

The Rare Association of Congenital Glaucoma, Giant Melanocytic Nevus, Alopecia, and Hypospadias in an Egyptian Child With Neurofibromatosis Type 1: A Case Report

research The rare association of congenital glaucoma, giant melanocytic nevus, alopecia, and hypospadias in an Egyptian child with neurofibromatosis type 1: a case report

September 2024 in “Egyptian Journal of Medical Human Genetics”

Consider NF1 in newborns with rare congenital anomalies.

research Discrimination of Dysplastic Nevi from Common Melanocytic Nevi by Cellular and Molecular Criteria

41 citations , July 2016 in “Journal of Investigative Dermatology”

Dysplastic nevi have unique gene expressions, making them distinct from common melanocytic nevi.

research Congenital atrichia associated with nevus flammeus: A rare association

2 citations , January 2014 in “Indian dermatology online journal”

A person was born with both a rare hairless condition and a type of birthmark, which is an uncommon combination.

research Hair loss in children.

6 citations , May 1993 in “Archives of Disease in Childhood”

Children's hair loss can be caused by many factors, including autoimmune diseases, emotional stress, genetics, and infections, with treatment and prognosis varying.

Cutaneous Features of Myotonic Dystrophy Types 1 and 2: Implications of Premature Aging and Vitamin D Homeostasis

research Cutaneous features of myotonic dystrophy types 1 and 2: Implication of premature aging and vitamin D homeostasis

18 citations , November 2016 in “Neuromuscular Disorders”

Patients with myotonic dystrophy often have skin problems that suggest early aging and vitamin D issues, and the severity of these problems is linked to their genetic condition and vitamin D levels.

research Perinevoid Alopecia: Report of Two Cases and Literature Review

1 citations , April 2023 in “Clinical, cosmetic and investigational dermatology”

Antigens from skin cells may cause hair loss in perinevoid alopecia.

research Epidermal Dysplasia and Abnormal Hair Follicles in Transgenic Mice Overexpressing Homeobox Gene MSX-2

49 citations , August 1999 in “Journal of Investigative Dermatology”

Overexpressing the MSX-2 gene in mice causes skin and hair growth issues.

research Index

November 2019 in “Harper's Textbook of Pediatric Dermatology”

The document is a detailed medical reference on skin and genetic disorders.

research Noninflammatory, Nonpruritic Alopecia of Horses

5 citations , October 2013 in “Veterinary Clinics of North America: Equine Practice”

Some horses lose hair without inflammation or itching due to various conditions, and while mainly a cosmetic issue, diagnosis requires examination and biopsies, and breeding is not advised if it's hereditary.

Congenital and Hereditary Skin Diseases in Bovines

research Congenital and Hereditary Skin Diseases

January 2018

Bovines can have rare inherited skin diseases with specific symptoms like hair loss, fragile skin, and abnormal porphyrin buildup.

TRPS1 Mutation Associated with Trichorhinophalangeal Syndrome Type 1 with 15 Supernumerary Teeth, Hypoplastic Mandibular Condyles with Slender Condylar Necks and Unique Hair Morphology

research TRPS1 mutation associated with trichorhinophalangeal syndrome type 1 with 15 supernumerary teeth, hypoplastic mandibular condyles with slender condylar necks and unique hair morphology

9 citations , April 2020 in “Journal of dermatology”

A person with a specific gene mutation had extra teeth, unique jaw and hair features not seen before in this condition.

research Hair loss among a group of Egyptian children

9 citations , January 2017 in “Journal of the Egyptian Women's Dermatologic Society (Print)”

Fungal infection was the main cause of hair loss in Egyptian children studied.

research Hair and nail disorders of childhood

7 citations , December 2008 in “Expert Review of Dermatology”

The document concludes that various childhood hair and nail disorders exist, some may improve on their own, and advances in genetics and immunology could enhance treatment and counseling.

research Congenital Atrichia: A Case Report

September 2023 in “International journal of science and healthcare research”

Genetic testing is crucial for diagnosing congenital atrichia, a rare condition causing irreversible hair loss.

research Hair Disorders

November 2019 in “Harper's Textbook of Pediatric Dermatology”

Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.

research Secondary Cicatricial and other Permanent Alopecias

June 2008 in “Springer eBooks”

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

The Frequency of Visceral and Phenotypic Markers in Patients with the Combination of Undifferentiated Connective Tissue Disease and Gastroesophageal Reflux Disease

research THE FREQUENCY OF VISCERAL AND PHENOTYPIC MARKERS IN PATIENTS WITH THE COMBINATION OF UNDIFFERENTIATED CONNECTIVE TISSUE DISEASE AND GASTROESOPHAGEAL REFLUX DISEASE

5 citations , January 2020 in “Wiadomości lekarskie (Warsaw Poland)”

Patients with both connective tissue disease and acid reflux are more likely to have certain symptoms and physical signs.

research Acute sensitivity of the oral mucosa to oncogenic K‐ras

12 citations , March 2011 in “Journal of pathology”

Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.

Hereditary, Congenital, and Acquired Alopecias in Dogs and Cats

research Hereditary, Congenital, and Acquired Alopecias

1 citations , January 2006 in “Elsevier eBooks”

The conclusion is that different types of hair loss in dogs and cats can be cosmetic or serious, and affected animals should not be bred.