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research Effect of Sun exposure-induced ferroptosis mechanisms on pathology and potential biological processes of primary melanoma by microarray data analysis

12 citations , September 2022 in “Frontiers in Genetics”

Enhancing CD8+ T cell function to induce ferroptosis in tumor cells may help treat skin melanoma.

research QS8: Analysis of the Whole Transcriptome in Breast Cancer Patients Undergoing Radiotherapy and Breast Reconstruction

July 2021 in “Plastic and reconstructive surgery. Global open”

Radiation therapy in breast cancer patients changes gene expression related to DNA damage, fibroblast growth, and hair follicle development, which could help improve treatment for radiation-induced fibrosis.

research Serum Epidermal Growth Factor Level and its Relation to Severity of Alopecia Areata

1 citations , January 2024 in “International Journal of Applied Biochemistry and Molecular Biology.”

Higher EGF levels are linked to more severe alopecia areata.

research Signal transducer and activator of transcription 5B deficiency due to a novel missense mutation in the coiled-coil domain

14 citations , September 2018 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.

research Ectodysplasin A (EDA) Signaling: From Skin Appendage to Multiple Diseases

6 citations , August 2022 in “International Journal of Molecular Sciences”

EDA signaling is linked to skin disorders, various cancers, and liver disease.

Enhanced Ectodysplasin-A Receptor Signaling Alters Multiple Fiber Characteristics to Produce the East Asian Hair Form

research Enhanced ectodysplasin-A receptor (EDAR) signaling alters multiple fiber characteristics to produce the East Asian hair form

98 citations , June 2008 in “Human mutation”

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

research ARTS, an unusual septin, regulates tumorigenesis by promoting apoptosis

10 citations , June 2022 in “Biomedicine & Pharmacotherapy”

ARTS helps stop tumors by promoting cell death.

research Deletion of vitamin D receptor with calcium sensing receptor in keratinocytes promotes epidermal tumorigenesis by limiting dna repair and oxidative stress response genes

March 2026 in “The Journal of Steroid Biochemistry and Molecular Biology”

Deleting vitamin D and calcium receptors in skin cells increases skin cancer risk by reducing DNA repair and stress response.

research Genetic effects of vascular endothelial growth factor and its receptor 2 on feather maturity in three chicken breeds

1 citations , January 2019 in “British Poultry Science”

VEGF and VEGFR-2 genes influence feather maturity, and specific genetic markers can improve chicken breeding.

research Genotoxic Agents: An Unexpected Effect on Healthy Epithelia

2 citations , December 2020 in “Developmental cell”

Chemotherapy drugs can cause abnormal growth and changes in healthy skin and gland cells.

research Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome

1 citations , May 2022 in “International journal of molecular sciences”

Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.

research Mandibulofacial dysostosis with alopecia results from ETAR gain-of-function mutations via allosteric effects on ligand binding

4 citations , January 2023 in “Journal of Clinical Investigation”

Specific mutations in a receptor cause facial abnormalities and hair loss.

research CtBP1 Overexpression in Keratinocytes Perturbs Skin Homeostasis

9 citations , November 2013 in “Journal of Investigative Dermatology”

Overexpressing CtBP1 in skin cells causes skin and hair problems.

research INDENTIFICATION OF GENES INVOLVED IN INHERITED ECTODERMAL DYSPLASIAS

January 2008

Mutations in specific genes cause different types of ectodermal dysplasias.

research Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis

76 citations , May 2011 in “Cell death and differentiation”

A20 protein is crucial for normal skin and hair development.

research A novel EDA variant that causes X-linked hypohidrotic ectodermal dysplasia in a Chinese family

August 2025 in “BMC Pregnancy and Childbirth”

A new EDA gene variant causes X-linked hypohidrotic ectodermal dysplasia in a Chinese family.

research 874 Elevated expression of osteopontin splice variants in nonmelanoma skin cancer compared to normal skin and adult keratinocytes

April 2018 in “Journal of Investigative Dermatology”

Nonmelanoma skin cancers have higher levels of certain osteopontin variants than normal skin.

research VEGF upregulates VEGF receptor-2 on human outer root sheath cells and stimulates proliferation through ERK pathway

23 citations , June 2012 in “Molecular Biology Reports”

VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.

research Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis

54 citations , February 2002 in “Carcinogenesis”

Increasing SSAT makes skin more prone to cancer.

PBX Homeobox 1 Enhances Hair Follicle Mesenchymal Stem Cell Proliferation and Reprogramming Through Activation of the AKT/Glycogen Synthase Kinase Signaling Pathway and Suppression of Apoptosis

research PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis

26 citations , August 2019 in “Stem Cell Research & Therapy”

PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.