January 2018 in “Biomedical Research (Aligarh)” Women with early-onset baldness should be checked for early bone loss, but bone density doesn't change with baldness severity.
December 2021 in “International Journal of Research in Dermatology” Men with early-onset hair loss have a higher risk of metabolic syndrome.
2 citations
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September 2013 in “Journal of Cosmetic Dermatology” Hair restoration combines drugs and follicular unit grafting for natural, long-lasting results.
October 2022 in “The Journal of Clinical Pharmacology” Men with early-onset hair loss have less cardiometabolic benefit from bromocriptine.
45 citations
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November 2009 in “British Journal of Dermatology” Women with early hair loss have higher blood pressure and aldosterone; screening and treatment may help.
7 citations
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September 2020 in “Journal of Cosmetic Dermatology” Smoking increases early hair loss risk in men; quitting may help prevent it.
87 citations
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May 2012 in “PLOS Genetics” Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.
15 citations
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August 2017 in “Scientific Reports” Young men with early hair loss have slightly worse blood sugar and fat levels, suggesting possible health risks and need for monitoring.
9 citations
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February 2020 in “International Journal of Endocrinology” Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.
December 2021 in “Biomarkers” Men with early baldness have similar heart risk factors as others, but certain proteins are linked to higher heart disease risk.
July 2020 in “Benha Journal of Applied Sciences” Young men with early hair loss and high SAA3 levels are at higher risk for heart disease.
May 2024 in “Journal of cosmetic dermatology” Low HDL-C, uric acid, and 25-hydroxyvitamin D are risk factors for early-onset male hair loss.
May 2022 in “The Journal of Clinical Pharmacology” Metformin reduces certain hormone levels in men with early-onset hair loss.
October 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Six new genes linked to early hair loss were found, which also surprisingly connect to Parkinson's disease and lower fertility.
October 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Six new genes linked to early hair loss were found, which also surprisingly connect to Parkinson's disease and lower fertility.
June 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Six new risk spots for early hair loss were found, which also link to Parkinson's disease and lower fertility. Two genes, FOXA2 and HDAC4, could be new treatment targets. Hair loss might also be connected to heart disease, metabolic syndrome, and prostate cancer.
195 citations
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June 2005 in “American Journal of Human Genetics” Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.
1 citations
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December 2017 in “Turkderm” People with a family history of hair loss are more likely to experience it, and the severity of hair loss is linked to insulin resistance. The connection between early hair loss and oxidative stress needs more investigation.
October 2021 in “QJM: An International Journal of Medicine” N-acetyl-cysteine improves hair growth and is safe for treating early male hair loss.
2 citations
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July 2021 in “Journal of Cardiovascular Pharmacology” Lisinopril improves heart health more in men with normal hair than those with early hair loss.
5 citations
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June 2021 in “Pharmacological Reports” Vitamin D may help reduce antibody levels in men with autoimmune thyroiditis and early-onset androgenic alopecia, but has no significant impact on thyroid function.
May 2025 in “Clinical Endocrinology” Metformin lowers prolactin in men with normal hair but not in those with early hair loss.
July 2022 in “British Journal of Dermatology” July 2022 in “British Journal of Dermatology” Eating a lot of soy might lower the chance of early hair loss in men likely to get it.
February 2026 in “Mendeley Data” Early hair loss may indicate higher risk of diabetes and heart disease.
2 citations
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January 2018 in “Annals of Dermatology” Early hair loss may be linked to metabolic syndrome.
January 2025 in “International Journal of Medicine in Developing Countries” Many in Saudi Arabia experience early hair loss but lack awareness of treatments.
August 2017 in “Revista de la Facultad de Ciencias Médicas (Quito)/Revista de la Facultad de Ciencias Médicas” Early-onset male baldness may indicate a higher risk of prostate cancer.
Men with higher body mass index (BMI) in Taiwan tend to have more severe hair loss.