44 citations
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April 2012 in “American Journal of Clinical Dermatology” Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
38 citations
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January 2012 in “Journal of Korean Medical Science” Early-onset alopecia, especially with a family history, leads to worse outcomes and more related health issues.
34 citations
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December 1991 in “Annals of the New York Academy of Sciences” The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.
25 citations
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March 2000 in “Journal of Endocrinological Investigation” Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
17 citations
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October 2005 in “Journal of Biological Chemistry” Early involution in Hirosaki hairless rats' mammary glands is linked to a unique modification of STAT5A.
16 citations
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January 2017 in “Asian journal of andrology/Asian Journal of Andrology” Men who start puberty later may have lower sperm quality and different hormone levels in adulthood.
9 citations
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February 2019 in “Journal of Clinical Research in Pediatric Endocrinology” Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.
7 citations
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March 2011 in “Expert Opinion on Drug Safety” Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.
5 citations
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May 2023 in “Science of the total environment” PFAS exposure in adolescence may delay puberty in females.
2 citations
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April 2021 in “PLoS ONE” Rural Bangladeshi girls mature later than peers in other low and middle-income countries due to poor nutrition and socioeconomic conditions.
1 citations
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January 2015 in “Journal of Dermatology and Venereology” Early hair loss may predict heart disease.
September 2025 in “Journal of Medical Sciences and Health” Early-onset male hair loss may be linked to higher cardiovascular risk.
January 2023 in “Integrative Journal of Medical Sciences” A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.
October 2018 in “Journal of Clinical Research in Pediatric Endocrinology” Children with classic congenital adrenal hyperplasia have thicker heart fat and more heart and blood vessel risk factors, especially if their condition is not well-controlled.
May 2017 in “InTech eBooks” Early treatment of children's hair loss, which can be caused by various factors, is important due to its emotional impact.
September 2002 in “Fertility and sterility” Female relatives of PCOS patients have a higher chance of showing PCOS symptoms.
855 citations
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June 2009 in “The Journal of Clinical Endocrinology & Metabolism” The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.
166 citations
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October 2018 in “Endocrine Reviews” Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.
January 2023 in “Zdravstvena zaštita” Aging-related hormone changes affect voice quality, especially during puberty, menstruation, pregnancy, and menopause.
139 citations
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July 1991 in “Journal of The American Academy of Dermatology” Understanding hair follicle anatomy helps diagnose hair disorders.
57 citations
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November 1987 in “Pediatric Dermatology” Children's hair grows in different types from before birth through puberty, with growth rates and characteristics varying by age, sex, and race.
45 citations
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March 2015 in “Clinical Endocrinology” Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.
11 citations
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July 2001 in “APMIS. Acta pathologica, microbiologica et immunologica Scandinavica./APMIS” Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.
5 citations
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July 2019 in “Nutrients” Low selenium intake may delay puberty in boys but not in girls.
5 citations
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February 2019 in “Neuroscience letters” Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.
1 citations
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January 2020 in “Elsevier eBooks” Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.
February 2025 in “Geriatrics and gerontology international/Geriatrics & gerontology international” Genetic testing is recommended for young patients showing signs like cataracts and hair changes to diagnose Werner syndrome early.
June 2006 in “Experimental Dermatology” Understanding skin patterns can help us learn about skin diseases and their treatments.
September 2017 in “Majallah-i taḥqīqāt-i ̒ulūm-i pizishkī-i Zāhidān” Androgenetic alopecia is a long-term, immune-related disorder that starts during puberty due to androgen secretion, and it might be improved with iron tablets, platelet transfusion, and anti-inflammation therapy.
October 2021 in “QJM: An International Journal of Medicine” N-acetyl-cysteine improves hair growth and is safe for treating early male hair loss.