1 citations
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May 2023 in “European Journal of Human Genetics” Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.
44 citations
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June 2015 in “British Journal of Pharmacology” Betulinic acid can help treat hepatitis C by stopping virus replication.
6 citations
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February 2009 in “Journal of Investigative Dermatology”
15 citations
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November 2022 in “Cell Death and Disease” CEP135 may predict cancer outcomes, and targeting PLK1 could help treat certain sarcomas.
January 2020 in “Medical journal of clinical trials & case studies” A 37-year-old male with severe skin and internal issues has a rare inherited skin condition called dystrophic epidermolysis bullosa.
5 citations
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January 2021 in “iScience” Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.
17 citations
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November 2017 in “PLoS ONE” Transplanted bone marrow cells actively move, form clusters, and grow after transplantation.
21 citations
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July 2004 in “British Journal of Dermatology” HPV type 56 can hide in hair follicles even without visible warts.
September 2019 in “Journal of Investigative Dermatology” Scientists used stem cells to create a model of the skin disease Epidermolysis Bullosa simplex, which helped them understand its molecular mechanisms and could aid in finding treatments.
July 2021 in “British Journal of Dermatology” Laser treatment for skin conditions VEN and ILVEN is effective and liked by patients.
December 2024 in “Kırıkkale Üniversitesi Tıp Fakültesi Dergisi” Chromosomal microarray analysis is important for diagnosing rare genetic variations and guiding treatment.
July 2024 in “Journal of Investigative Dermatology” CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.
78 citations
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January 2013 in “Brachytherapy” HDR electronic brachytherapy effectively treats nonmelanoma skin cancer with good cosmetic results and minimal side effects.
34 citations
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November 2008 in “British Journal of Dermatology” Hair extensions can cause hair loss and scalp damage, and these problems might be more common than people realize.
40 citations
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October 2009 in “Journal of Biomedical Nanotechnology” Pyrene excimer nucleic acid probes are promising for detecting biomolecules accurately with potential for biological research and drug screening.
November 2022 in “Journal of Investigative Dermatology” Most Recessive Dystrophic Epidermolysis Bullosa patients with a specific mutation likely have Sephardic ancestry from about 500 years ago.
TBX3 gene affects horse coat color, with higher expression in darker areas.
November 2025 in “Clinical and Translational Medicine” DNAJB9 cfRNA could help diagnose and treat female hair loss.
January 2026 in “Journal of Radiation Research” 53BP1 focus analysis in hair cells can help estimate radiation doses.
23 citations
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February 2019 in “International Journal of Molecular Sciences” Activin B can boost hair growth by promoting cell proliferation and cell cycle progression.
September 2019 in “Journal of Investigative Dermatology” Targeted therapy with Ustekinumab significantly improved a skin condition called ILVEN, which is caused by mutations in the CARD14 gene.
November 2024 in “NeoReviews” An extremely low-birthweight infant had a rare genetic skin disease and died despite treatment.
14 citations
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January 2016 in “Experimental and molecular pathology” Giving immune serum from vaccinated mice to mice without T cells prevents infection and tumor growth.
44 citations
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January 2017 in “Journal of Investigative Dermatology” Mutations in the KLHL24 gene cause skin blistering in epidermolysis bullosa simplex.
48 citations
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September 2011 in “British Journal of Dermatology” Epigenetic changes in blood cells may contribute to alopecia areata.
9 citations
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December 1996 in “Cell Biology and Toxicology” Hair follicle cells produce VEGF, which can promote blood vessel cell growth and movement.
January 2011 in “Anhui nongye kexue” The vector successfully directed specific gene expression in hair follicles.
34 citations
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November 1998 in “Journal of Investigative Dermatology” A common mutation in the hHb6 gene is linked to monilethrix, but other factors may also play a role.
6 citations
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May 2003 in “PubMed” Small amounts of DNA can be found in the hair shaft, especially near the root, but it decreases with hair treatments and washing.
September 2024 in “Journal of Medicine and Life” A specific gene mutation causes a severe skin disorder in a family.