151 citations
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November 2014 in “Annual Review of Animal Biosciences” Feathers are crucial for understanding bird evolution, development, and have inspired biomimetic research.
32 citations
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February 2019 in “eLife” BMP signaling is essential for the development of touch domes.
6 citations
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May 2024 in “Developmental Biology” January 2006 in “Zhongguo bingli shengli zazhi” Murine epidermal stem cells can develop into skin structures without rejection when implanted.
25 citations
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September 2006 in “Birth Defects Research” Different processes create patterns in skin and things like hair and feathers.
173 citations
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August 2015 in “Developmental cell” The study identified unique genes in hair follicle cells and their environment, suggesting these genes help organize cells for hair growth.
19 citations
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April 1999 in “British Journal of Dermatology” Keratin 2e shows a unique pattern in developing fetal skin, different from other keratins.
18 citations
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January 2018 in “Advances in experimental medicine and biology” Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.
10 citations
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January 1987 in “PubMed” Thyroid hormone and epidermal growth factor affect hair angle, tooth eruption, and ear development in rats.
218 citations
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April 2008 in “Genes & Development” Skin stem cells help repair damage and maintain healthy skin.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists created skin-like structures from stem cells that include features like hair and sweat glands.
17 citations
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August 2012 in “Journal of Medical Genetics” A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.
36 citations
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January 1994 in “Cell and Tissue Research” December 2004 in “Differentiation”
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists improved how to make skin-like structures from stem cells using special gels and a device that controls growth signals, leading to better hair and skin features.
EGF and EGFR are important for goat skin development, increasing from weeks 6 to 21.
January 2008 in “Yearbook of Dermatology and Dermatologic Surgery” One type of progenitor cell can maintain normal skin in mice.
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.
May 2026 in “The EMBO Journal” Feather follicles form through specific cellular flows and mechanical changes in the skin.
August 2023 in “Journal of Investigative Dermatology” Skin organoids can regenerate hair by forming specific cell units with certain signals.
December 2012 in “Journal of dermatological science” Langerhans cells and melanocytes migrate to the skin and hair follicles during early human development.
64 citations
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January 1995 in “Cells Tissues Organs” Merkel cells develop independently of nerves and are linked to specific hair follicles in mice.
January 2004 in “Linchuang pifuke zazhi” α- and γ-catenins help develop fetal skin by 23 weeks.
112 citations
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August 1984 in “Journal of Investigative Dermatology” 83 citations
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February 1991 in “Development” Fos protein is crucial for cell transition to cornification in keratinized tissues.
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
20 citations
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September 2004 in “Journal of Anatomy” The inner root sheath evolved to help hair grow safely through the skin in mammals.
January 2000 in “Medical Entomology and Zoology” 2 citations
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January 1989 Researchers developed a method to grow skin-like tissue from hair cells.
106 citations
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September 2010 in “Stem cells” Skin-derived precursors in hair follicles come from different origins but function similarly.