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A patient with a PLEC mutation has epidermolysis bullosa, muscular dystrophy, and myasthenia gravis, which improved with steroid treatment.

The Trichodysplasia spinulosa virus protein can cause abnormal hair growth in mice.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

New genes and pathways are important for testosterone production and male sexual development.

Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.

17β-estradiol boosts APE1/Ref-1 secretion in cells and mice via a calcium-dependent pathway.

New mutations in the EBP gene cause CDPX2, affecting bones, skin, eyes, and hair, with females generally less affected than males.

New RIPK4 gene mutations were found to cause a type of skin and limb birth defect.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.

Birds can regenerate inner ear cells using specific gene pathways, unlike mammals.

Claudin expression changes help the skin respond to injury.

Carriers of a specific gene mutation have subtle skin changes without visible symptoms.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.

Different PADI isoforms help cells develop diverse functions.

The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.

Controlling Tslp can improve health in AEC syndrome patients.

Vitamin D receptor helps control hair growth genes in skin cells.

The PP2A-B55α protein is essential for brain and skin development in embryos.

ERK activation spreads between cells, influencing cell division and wound healing.

Scientists used stem cells to create a model of the skin disease Epidermolysis Bullosa simplex, which helped them understand its molecular mechanisms and could aid in finding treatments.

Alopecia areata patients show unique protein activity patterns, suggesting imbalanced signaling pathways.

The Engrailed-1 gene plays a key role in the development of sweat glands in mice.

BMP receptor IA is essential for proper hair cell differentiation in mice.