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The TRPV3 channel structure changes linked to severe itch and hyperkeratosis were identified using cryo-EM.

ΔNp63α helps control a protein that stops cancer cells from spreading.

The Engrailed-1 gene plays a key role in the development of sweat glands in mice.

Scientists developed a new way to study mutations in a skin condition using blood cells, which may help diagnose and treat the disease.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

The vitamin D receptor helps control hair growth and may protect against certain skin tumors.

Rat dermal papilla cells have unique properties and interact differently with their environment compared to other skin cells.

RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.

Claudin expression changes help the skin respond to injury.

Human adrenals and gonads have a unique enzyme for steroid hormone production.

The STRIPAK complex is crucial for skin cell organization and creating a functional skin barrier.

Trps1 plays a key role in hair follicle development and cycling.

Cholesteatoma shows abnormal and increased EGF receptor expression, indicating its rapid growth.

Trichothiodystrophy hair is structurally abnormal with protein and organization issues.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Neutrophils quickly respond to skin injury.

Vitamin D helps skin stem cells heal wounds by working with a key skin protein.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Trps1 is essential for proper hair follicle development.

The specific skin disease variant p.(Arg2000Trp) in plectin can cause a wide range of symptoms, which should be considered when diagnosing patients.

Axolotl spinal cord regeneration may be controlled by a specific signal affecting cell sensitivity and diffusion.

The glucocorticoid receptor helps protect skin from tumors and other issues.

DAB labeling effectively identifies collagen type III and PDGFR in horse skin, but may show false positives.

DPP4, a molecule in skin, helps heal large wounds and regrow hair follicles when its levels are reduced.

Oxytocin receptors are found in skin cells near touch and pain neurons.

PrPC is important for neural differentiation in cattle and mouse embryonic stem cells.

Blocking certain pathways with kinase inhibitors may help treat cutaneous lupus erythematosus.

Scientists used stem cells to create a model of the skin disease Epidermolysis Bullosa simplex, which helped them understand its molecular mechanisms and could aid in finding treatments.

Dysplastic nevi have unique gene expressions, making them distinct from common melanocytic nevi.

TRPS1 is crucial for bone, kidney, and hair follicle development.