108 citations
,
January 2003 in “Journal of Cosmetic Dermatology” Wrinkles form due to structural skin changes and vary in type and treatment response.
3 citations
,
September 2019 in “Skin appendage disorders” Women with Frontal Fibrosing Alopecia have more wrinkles near their ears than similar aged women without the condition.
52 citations
,
November 2006 in “International Journal of Cosmetic Science” Different types of wrinkles need specific treatments.
41 citations
,
May 2018 in “Nutrition and healthy aging” Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
20 citations
,
June 2014 in “Pharmaceutical research” Using both hyaluronic acid compounds together improves skin hydration and reduces wrinkles better than using one alone.
November 2022 in “Journal of Investigative Dermatology” The LED light therapy mask improved skin elasticity and reduced signs of aging in a test and in women aged 40-60.
3 citations
,
May 2011 in “Practice nursing” As skin ages, it gets thinner, paler, and more wrinkled, and protection and care like sunblock and moisturizers are important.
January 2000 in “Elsevier eBooks” Menopause can cause skin to become dry, less elastic, and more wrinkled due to lower estrogen levels.
September 2022 in “The Egyptian Journal of Hospital Medicine” Microneedling is an effective, safe, and affordable method to treat skin conditions like scars and wrinkles.
4 citations
,
November 2023 in “Journal of Cosmetic Dermatology” Negative pressure fractional microneedle radiofrequency effectively and safely reduces periorbital aging signs.
9 citations
,
February 2021 in “Frontiers in Cell and Developmental Biology” Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
3 citations
,
July 2023 in “Plastic and reconstructive surgery/PSEF CD journals” Nanofat grafting improves scars, rejuvenates skin, and may help hair growth safely, but more research is needed.
11 citations
,
January 2005 in “Brazilian Journal of Medical and Biological Research” Hairless USP mice have enlarged skin cysts as they age.
September 2017 in “Journal of Investigative Dermatology” Aging causes sweat glands to shrink and move upward, leading to less elastic skin and more wrinkles.
June 1996 in “Journal of Dermatological Science” Vitamin D3 applied to mouse skin caused more wrinkles and sagging due to changes in the skin's outer layer.
March 2024 in “Intisari Sains Medis” PRP injections improve periorbital wrinkles and show promise as a treatment.
4 citations
,
July 2024 in “Cureus” The treatment improved neck wrinkles and skin laxity.
19 citations
,
October 2020 in “Biomedical Microdevices” Derma rollers show promise for skin improvement and drug delivery, but more research is needed on their safety and effectiveness.
10 citations
,
November 2017 in “Dermatologic Clinics” More men are getting cosmetic procedures, mainly for aging, hair loss, and to keep masculine features, with growing interest in both surgical and noninvasive treatments.
2 citations
,
November 2014 Common cosmetic dermatology techniques improve skin damaged by the sun and aging.
March 2026 in “Food, Nutrition and Health.” Collagen peptides may help reduce skin aging by improving elasticity and hydration.
Microneedle technology is effective for skin rejuvenation and enhancing cosmeceutical delivery, with ongoing innovation and increasing commercialization.
17 citations
,
February 2023 in “Cosmetics” 3D printed hollow microneedles could effectively treat skin wrinkles with fewer side effects.
November 2025 in “BMC Genomics” Wrinkled skin in Xiang pigs is linked to gene changes related to oxidative stress and the extracellular matrix.
120 citations
,
July 2005 in “Dermatologic surgery” Niacinamide improves aging skin and is safe for use in cosmetics.
27 citations
,
May 2016 in “Dermatologic Surgery” Male faces age with more wrinkles and hair loss, influenced by both body changes and environmental factors.
22 citations
,
November 2024 in “Planta” Aromatic plants can naturally help prevent skin aging and improve skin health.
6 citations
,
January 2016 in “Menopause” Estrogen deficiency, like after menopause or certain surgeries, leads to faster skin aging and health issues.
5 citations
,
July 2022 in “Frontiers in Medicine” Combining microneedle-delivered ECM and radiofrequency improves skin elasticity and thickness more than ECM alone.
2 citations
,
September 2004 in “International Journal of Cosmetic Science” Hair quality is genetically determined and linked to its composition and strength.