research Combination Treatment with Methotrexate for Severe Alopecia Areata
Combining methotrexate and corticosteroids can effectively regrow hair in severe alopecia areata.
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research Hair Disorders
Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.
research Síndrome dos ovários policísticos: correlação dos fenótipos com as manifestações metabólicas
Older age, obesity, hirsutism, and having children increase metabolic risk in women with PCOS.
research Deciphering principles of morphogenesis from temporal and spatial patterns on the integument
The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
research In Situ Self-Assembling Liver Spheroids with Synthetic Nanoscaffolds for Preclinical Drug Screening Applications
PCL nanoscaffold-based liver spheroids are effective for drug screening and studying liver toxicity.
research PINK1 deficiency rewires early immune responses in a mouse model of Parkinson’s disease triggered by intestinal infection
PINK1 is important for controlling gut immune responses linked to early Parkinson's disease.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research Long-term dutasteride therapy in men with benign prostatic hyperplasia alters glucose and lipid profiles and increases severity of erectile dysfunction
Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.
research Current standards in the diagnostics and therapy of hair diseases - hair consultation
The document concludes that proper diagnosis and evidence-based treatments are crucial for managing hair diseases, and psychological support for patients is important.
research Abstracts Presented at the 12th Joint Meeting of the International Society of Dermatopathology, March 4-5, 2009, Marines Memorial Club & Hotel, San Francisco, CA, USA
Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.
research Is early onset androgenetic alopecia related to hyperuricemia? A case control study
Men with early onset hair loss are more likely to have high uric acid levels.
research Oxidative stress and autoimmune skin disease
Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.
research Multifaceted roles of superoxide dismutases (SODs) in cellular homeostasis and cancer progression: Redox regulation and therapeutic implications
Superoxide dismutases help balance cell stress and may aid cancer treatment.
research Cutaneous application of α-methylspermidine activates the growth of resting hair follicles in mice
Putting α-methylspermidine on mouse skin can start hair growth.
research Post-COVID-19 syndrome and quality of life impairment in severe COVID-19 Mexican patients
Most severe COVID-19 patients in Mexico experienced long-lasting symptoms that worsened their quality of life.
research Reversing Gray Hair: Inspiring the Development of New Therapies Through Research on Hair Pigmentation and Repigmentation Progress
Gray hair can potentially be reversed, leading to new treatments.
research Insights into the context-dependent immunological roles of the CXCL12–CXCR4 axis in alopecia
Blocking the CXCL12–CXCR4 axis may help treat hair loss in alopecia.
research Hypoxia-Derived Mesenchymal Stem Cell Exosomes Downregulate CXCL12 and Upregulate IL-10 Expression in a Murine Model of Androgenic Alopecia
EH-MSCs may help treat hair loss by reducing inflammation.
research Finasteride inhibited brain dopaminergic system and open-field behaviors in adolescent male rats
Finasteride affects young male rats' brain function and behavior negatively.
research Parathyroid adenoma with coeliac disease: primary or quaternary hyperparathyroidism? Gruczolak przytarczyc i choroba trzewna: pierwotna czy czwartorzędowa nadczynność przytarczyc?
A gluten-free diet and removing the parathyroid adenoma helped a girl with coeliac disease and high calcium levels start puberty.
research Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities
Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.
research Increased DHEAS and Decreased Total Testosterone Serum Levels in a Subset of Men with Early-Onset Androgenetic Alopecia: Does a Male PCOS-Equivalent Exist?
Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.
research The Rotterdam Study: 2018 update on objectives, design and main results
The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
research A wearable and stretchable dual-wavelength LED device for home care of chronic infected wounds
A new wearable LED device helps heal chronic infected wounds at home.
research Diagnosis and treatments of hirsutism: where are we?
Effective treatments for excessive hair growth in women include creams, laser therapy, and medications, with the choice depending on individual needs and potential side effects.
research De Novo Design of Anti-Aging Peptides
New peptides can delay aging and improve cell function.
research Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase
The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.
research Eph/ephrin signaling in epidermal differentiation and disease
Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
research Molecular Mechanisms Responsible for Therapeutic Potential of Mesenchymal Stem Cell-Derived Secretome
The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.
research SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder
Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.