October 2020 in “Journal of the American Society of Nephrology” Drospirenone can hide symptoms of certain hormonal disorders, complicating diagnosis.
March 2020 in “Endocrinology research and practice.” Treating prolactinoma doesn't significantly affect hirsutism or cause high androgen levels.
April 2019 in “Journal of the Endocrine Society” Bilateral ovarian hyperthecosis is a rare but treatable cause of increased facial hair in postmenopausal women.
October 2022 in “Biomolecules” Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.
January 2016 in “Medicinski Podmladak” Finasteride may increase anxiety in bright spaces.
3 citations
,
August 2025 in “International Journal of Molecular Sciences” Women with PCOS have higher levels of thyroid autoantibodies.
317 citations
,
April 2018 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.
292 citations
,
April 2024 in “Nature Reviews Disease Primers” Early diagnosis and treatment of PCOS are crucial to reduce health risks and costs.
44 citations
,
September 2020 in “International Journal of Molecular Sciences” New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.
7 citations
,
September 2024 in “International Journal of Molecular Sciences” PCOS involves high 11-oxygenated androgens and BPA may worsen it, while IH is not inflammatory.
7 citations
,
July 2024 in “Frontiers in Immunology” COVID-19 can increase the risk of hair loss, especially in people over 40.
5 citations
,
April 2024 in “ACS Chemical Neuroscience” A new method accurately measures nine neuroactive steroids in small blood samples, helping to study brain diseases.
3 citations
,
January 2024 in “Revista da Associação Médica Brasileira” Women with PCOS are more likely to have depression and anxiety.
3 citations
,
February 2021 in “Pediatric rheumatology online journal” A girl with lupus and trisomy X has a higher risk of bone problems like avascular necrosis and osteoporosis.
1 citations
,
July 2025 in “Middle East Fertility Society Journal” Autoimmune markers may help diagnose and manage PCOS.
1 citations
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June 2023 in “Reproduction” Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.
1 citations
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August 2019 in “Journal of pediatric & adolescent gynecology” A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.
February 2026 in “PubMed” Finasteride withdrawal causes anxiety-like behavior in male rats.
January 2026 in “Hormones and Behavior” Pregnancy affects fear memory and brain activity in female rats.
January 2024 in “Medicina” Statins may help treat PCOS by lowering androgen levels and improving cholesterol.
September 2023 in “F&S reports” PCOS may increase the risk of mental health issues like depression and anxiety.
September 2024 in “Journal of Clinical and Translational Endocrinology Case Reports” Biotin can interfere with lab tests, causing misdiagnosis.
June 2020 in “AACE clinical case reports” A woman's severe male hormone excess was caused by a small, hard-to-find ovarian tumor.
May 2021 in “Journal of the Endocrine Society” The 18-year-old girl likely has a condition called müllerian agenesis, which caused her to not have a uterus and experience no menstrual periods.
May 2023 in “The journal of sexual medicine” Ovarian Hyperthecosis caused hypersexuality in an older woman and was successfully treated with surgery.
October 2014 in “Journal of Minimally Invasive Gynecology” Genetic testing for cancer risk can lead to early and life-saving treatments in people without symptoms.
269 citations
,
May 2002 in “Journal of Neuroscience” Stress increases neurosteroids that help prevent seizures.
69 citations
,
December 2005 in “Nature Clinical Practice Endocrinology & Metabolism” Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.
65 citations
,
October 2008 in “Journal of Neuroendocrinology”
49 citations
,
May 2018 in “Endocrine” Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.