42 citations
,
March 2008 in “Molecular and Cellular Endocrinology” Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
9 citations
,
March 2019 in “Scientific reports” Temporary ROS production in cultured human hair follicles promotes growth and stem cell activation.
4 citations
,
May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” ELL is crucial for gene transcription related to skin cell growth.
26 citations
,
February 2012 in “Journal of Investigative Dermatology” Human hair follicle cells can be successfully transformed into different types of cells, but not more efficiently than other adult cells.
8 citations
,
May 2013 in “Journal of Investigative Dermatology” Different problems with hair stem cell renewal can lead to hair loss.
835 citations
,
October 2008 in “Nature Genetics” Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
60 citations
,
June 2019 in “Ageing Research Reviews” Fat from the body can help improve hair growth and scars when used in skin treatments.
47 citations
,
September 2015 in “Cell Cycle” Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.
22 citations
,
October 2011 in “Bone” Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” MOF controls skin development by regulating genes for mitochondria and cilia.
1 citations
,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
11 citations
,
December 2018 in “Bone” Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.
1 citations
,
December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Sox9 levels in brain stem cells affect whether they stay as stem cells or become neurons.
64 citations
,
August 2013 in “Mayo Clinic Proceedings” Wound healing insights can improve regenerative medicine.
71 citations
,
October 2017 in “Journal of Investigative Dermatology” PPAR-γ agonists like pioglitazone may help manage lichen planopilaris but don't fully reverse scarring.
17 citations
,
November 2023 in “Journal of Biological Engineering” Antler stem cell exosomes improve wound healing and reduce scarring.
April 2018 in “Journal of Investigative Dermatology” BMP signaling is important for skin color, affecting melanin production, pigment spread, and cell movement.
May 2018 in “Journal of Investigative Dermatology” Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.
24 citations
,
August 2021 in “Biologics” Stem cell therapy shows promise in improving burn wound healing.
January 2012 in “Journal of Investigative Dermatology” Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.
8 citations
,
October 2021 in “Stem Cell Research & Therapy” Mesenchymal stem cells may effectively treat and prevent allergic skin conditions.
9 citations
,
August 2015 in “Tissue Engineering and Regenerative Medicine” Human skin cell byproducts can potentially be used to treat hair loss and promote hair growth.
April 2018 in “Journal of Investigative Dermatology” The research found that a specific skin cell type not only triggers hair growth but also controls hair color, and that aging can lead to hair loss and color changes.
January 2006 in “Advances in developmental biology” The Hairless gene is crucial for healthy skin and hair growth.
February 2024 in “Plastic and Reconstructive Surgery – Global Open” Stem cell therapies show promise for hair regrowth in androgenetic alopecia.
63 citations
,
November 2012 in “Journal of Cellular Biochemistry” Runx1 affects hair growth, cancer development, and autoimmune diseases in epithelial tissues.
223 citations
,
January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
128 citations
,
August 2015 in “Cell Stem Cell” Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
12 citations
,
February 2025 in “Scientific Reports” MSC-EVs and UCB-EVs improve skin wound healing and reduce scarring.
10 citations
,
May 2020 in “Frontiers in cell and developmental biology” MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.