research Clinicopathological Features of Frontal Fibrosing Alopecia (FFA) in 26 females: A Retrospective Study
Frontal fibrosing alopecia mainly affects women over 50, causing hair loss and specific skin changes.
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540-570 / 1000+ results research LB708 ILC1-like innate lymphocytes in human autoimmunity: Lessons from Alopecia Areata
ILC1-like cells can cause alopecia areata by disrupting hair follicle immunity, suggesting a new treatment approach.
research Prepubertal Fibrosing Alopecia in a Pattern Distribution
FAPD in children may not depend on androgens and should be treated with anti-inflammatory measures and minoxidil.
research In vitro culture of murine fetal epidermal stem cell and its relationship with the regeneration of hair follicle
Murine fetal epidermal stem cells can help regenerate hair follicles.
research Alymphoid cystic thymic dysgenesis - FOXN1 gene mutation: a rare case report of two siblings
Two siblings had a rare immune disorder caused by a FOXN1 gene mutation.
research Transcription factor FOXC1 positively regulates SFRP1 expression in androgenetic alopecia
FOXC1 boosts SFRP1 in hair loss, suggesting new treatments.
research Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis
Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.
research Author response: Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells
IL-1 and IL-7 help activate cells that boost hair follicle stem cell growth, aiding wound healing.
research Inhibition of TNF-α-Induced Collagen Degradation and Oxidative Damage by Centipeda minima and Brevilin A in Human Dermal Fibroblasts
Centipeda minima and brevilin A protect skin cells from damage and aging.
research An ERK-dependent molecular switch antagonizes fibrosis and promotes regeneration in spiny mice ( Acomys )
High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
research LHX2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth
LHX2 is essential for hair follicle development, controlled by NF-κB and TGFβ2 signaling.
research Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFα expression in transgenic mice
research Breast cancer resistance protein identifies clonogenic keratinocytes in human interfollicular epidermis
ABCG2 protein marks stem-like skin cells in human epidermis.
research Induction of Hard Keratin Expression in Non-Nail-Matrical Keratinocytes by Nail-Matrical Fibroblasts through Epithelial-Mesenchymal Interactions
Nail-matrical fibroblasts can make non-nail cells produce hard keratin, useful for nail repair.
research Rare presentation of disseminated follicular lymphoma as an ill-defined reticular patch over the scalp and forehead
A woman with lymphoma had a rare skin rash on her scalp and forehead, which was hard to diagnose but responded well to treatment.
research Amphiregulin in Fibrotic Diseases and Cancer
Targeting amphiregulin may improve treatment for fibrotic diseases and cancer.
research Cutaneous Lupus Erythematosus Presenting as Frontal Fibrosing Alopecia: Report of 2 Patients
Two patients with skin lupus were mistakenly thought to have a different scalp condition but improved with lupus treatment.
research Human keratinocytes derived from the bulge region of hair follicles are refractory to differentiation
Hair follicle cells resist turning into skin cells.
research Cooperation of TGF‐β and FGF signalling pathways in skin development
TGF-β and FGF pathways are crucial for skin development and regeneration.
research 861 EGFR/MEK inhibitor therapy induces partial hair follicle immune privilege collapse in vivo and ex vivo
research Keratinocyte integrin α3β1 induces expression of the macrophage stimulating factor, CSF-1, through a YAP/TEAD-dependent mechanism.
research Recombinant Human Annexin A5 Ameliorates Localized Scleroderma by Inhibiting the Activation of Fibroblasts and Macrophages
Recombinant Human Annexin A5 may help treat localized scleroderma by reducing skin thickening and inflammation.
research The potential role of fibroblast‐derived multi‐peptide factors in activation of growth factors and β‐Catenin in hair follicle cells
Multi-peptide factors from fibroblasts may stimulate hair growth by increasing growth factors and β-catenin in hair cells.
research Single‐Cell Analysis of Late‐Stage Wound‐Induced Hair Follicle Neogenesis Reveals Keratinocyte Heterogeneity and Enrichment of Infundibular Basal Keratinocytes
Large wounds have more infundibular basal keratinocytes, aiding hair follicle regeneration.
research 1330 Flexible fate determination ensures robust differentiation in the skin hair follicle
Hair follicle stem cells can change their role to ensure proper hair development.
research A case report of inflammatory nonscarring alopecia associated with the epidermal growth factor receptor inhibitor erlotinib
Erlotinib can cause nonscarring hair loss and itchy skin.
research 415 IL-17C: Checkpoint in innate skin immunology
IL-17C is important in inflammatory skin diseases and could be a target for treatment.
research Acute hair loss on the limbs in frontal fibrosing alopecia: a clinicopathological study of two cases
Frontal fibrosing alopecia can cause sudden hair loss on limbs, similar to scalp hair loss.
research Frontal Fibrosing Alopecia
Frontal fibrosing alopecia is a scarring hair loss condition mainly affecting postmenopausal women, with unclear causes.
research さまざまな臓器からの培養線維芽細胞による毛包誘導
Cells from skin and lung can help regenerate hair follicles.