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research Thyroid-Stimulating Hormone, a Novel, Locally Produced Modulator of Human Epidermal Functions, Is Regulated by Thyrotropin-Releasing Hormone and Thyroid Hormones

105 citations , February 2010 in “Endocrinology”

The skin produces and responds to thyroid-stimulating hormone, which is controlled by other thyroid-related hormones.

Cloning of a Functional Vitamin D Receptor from the Lamprey, an Ancient Vertebrate Lacking a Calcified Skeleton and Teeth

research Cloning of a Functional Vitamin D Receptor from the Lamprey (Petromyzon marinus), an Ancient Vertebrate Lacking a Calcified Skeleton and Teeth

104 citations , May 2003 in “Endocrinology”

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

research Topical Thyroid Hormone Accelerates Wound Healing in Mice

99 citations , June 2005 in “Endocrinology”

Applying thyroid hormone T3 speeds up wound healing in mice.

research The Antiandrogenic Action of 4–Androsten–3–one–17β– Carboxylic Acid and Its Methyl Ester on Hamster Flank Organ1

87 citations , April 1973 in “Endocrinology”

The chemicals 17βC and its methyl ester can block the effects of testosterone on hamster skin but not the effects of DHT.

research Hairless Suppresses Vitamin D Receptor Transactivation in Human Keratinocytes

78 citations , November 2005 in “Endocrinology”

Hairless protein can block vitamin D activation in skin cells.

research Structure of human type II 5 alpha-reductase gene

76 citations , September 1992 in “Endocrinology”

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice

research Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice*

73 citations , June 2001 in “Endocrinology”

Prolactin affects when mice shed and grow hair.

research Ligand-Dependent Actions of the Vitamin D Receptor Are Required for Activation of TGF-β Signaling during the Inflammatory Response to Cutaneous Injury

56 citations , November 2012 in “Endocrinology”

Vitamin D receptor is essential for proper skin healing after injury.

research 5α-Reductase Type 2 Regulates Glucocorticoid Action and Metabolic Phenotype in Human Hepatocytes

54 citations , May 2015 in “Endocrinology”

Manipulating 5α-reductase type 2 can affect liver fat production and glucocorticoid effects.

research Nipple Differentiation in Fetal Male Rats Treated with an Inhibitor of the Enzyme 5α-Reductase: Definition of a Selective Role for Dihydrotestosterone*

53 citations , January 1986 in “Endocrinology”

Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.

research Ectoderm-Targeted Overexpression of the Glucocorticoid Receptor Induces Hypohidrotic Ectodermal Dysplasia

46 citations , March 2005 in “Endocrinology”

Overexpression of the glucocorticoid receptor in mice causes developmental defects similar to ectodermal dysplasia.

Animal Models and the Developmental Origins of Polycystic Ovary Syndrome: Increasing Evidence for the Role of Androgens in Programming Reproductive and Metabolic Dysfunction

research Animal Models and the Developmental Origins of Polycystic Ovary Syndrome: Increasing Evidence for the Role of Androgens in Programming Reproductive and Metabolic Dysfunction

44 citations , May 2012 in “Endocrinology”

High levels of androgens during early development may cause PCOS-like symptoms.

research Cortisol Enhances the Expression of mac25/Insulin-Like Growth Factor-Binding Protein-Related Protein-1 in Cultured Osteoblasts**This work was supported by NIDDK Grant DK-45227 and a scholarship (to R.C.P.) from Fundacao Coordenacao de Aperfeicoa mento de Pessoal de Nivel Superior (CAPES), Universidade de Sao Paulo (Sao Paulo, Brazil).

43 citations , January 1999 in “Endocrinology”

Cortisol increases a specific protein in bone cells, which may help explain its negative effects on bone.

Vitamin D3 Analogs Stimulate Hair Growth in Nude Mice

research Vitamin D₃Analogs Stimulate Hair Growth in Nude Mice

40 citations , October 2002 in “Endocrinology”

Vitamin D3 analogs can promote hair growth in mice genetically prone to hair loss.

research Mrp3, a Mitogen-Regulated Protein/Proliferin Gene Expressed in Wound Healing and in Hair Follicles*

34 citations , May 2001 in “Endocrinology”

Mrp3 helps in wound healing and hair growth.

Stimulating Effect of Adrenalectomy on Hair Growth and Melanin Deposition in Black Rats Fed Diets Adequate and Deficient in the Filtrate Factors of Vitamin B1

research STIMULATING EFFECT OF ADRENALECTOMY ON HAIR GROWTH AND MELANIN DEPOSITION IN BLACK RATS FED DIETS ADEQUATE AND DEFICIENT IN THE FILTRATE FACTORS OF VITAMIN B¹

34 citations , January 1943 in “Endocrinology”

Adrenalectomy boosts hair growth and melanin in black rats, even with vitamin B¹ deficiency.

Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque

research Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque¹

33 citations , January 1997 in “Endocrinology”

Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.

research HSD3B1 Genotypes Conferring Adrenal-Restrictive and Adrenal-Permissive Phenotypes in Prostate Cancer and Beyond

30 citations , July 2019 in “Endocrinology”

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

research Evaluation of Keratinocyte Proliferation and Differentiation in Vitamin D Receptor Knockout Mice

29 citations , June 2000 in “Endocrinology”

Alopecia in VDR knockout mice is due to impaired hair cycle initiation, not keratinocyte issues.

research Combined Deletion of the Vitamin D Receptor and Calcium-Sensing Receptor Delays Wound Re-epithelialization

28 citations , March 2017 in “Endocrinology”

Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.

An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess

research An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess

27 citations , December 2013 in “Endocrinology”

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

The Effects of Synthetic and Natural Hormones of the Adrenal Cortex on Melanin Deposition in Adrenalectomized Black Rats Fed Diets Adequate and Deficient in Vitamin B1

research THE EFFECTS OF THE SYNTHETIC AND NATURAL HORMONE OF THE ADRENAL CORTEX ON MELANIN DEPOSITION IN ADRENALECTOMIZED BLACK RATS FED DIETS ADEQUATE AND DEFICIENT IN THE FILTRATE FACTORS OF VITAMIN B¹

27 citations , October 1945 in “Endocrinology”

Synthetic hormone treatment reduces melanin and hair growth in rats.

research A Topical Parathyroid Hormone/Parathyroid Hormone-Related Peptide Receptor Antagonist Stimulates Hair Growth in Mice

26 citations , December 2006 in “Endocrinology”

A cream with a specific hormone blocker increases hair growth in mice.

research A Humanized Mouse Model of Hereditary 1,25-Dihydroxyvitamin D–Resistant Rickets Without Alopecia

25 citations , August 2014 in “Endocrinology”

Researchers created a mouse model of a type of rickets that does not cause hair loss.

research Targeting Expression of the Human Vitamin D Receptor to the Keratinocytes of Vitamin D Receptor Null Mice Prevents Alopecia

21 citations , December 2001 in “Endocrinology”

Expressing the human vitamin D receptor in skin cells prevents hair loss in certain mice.

research In Vitroandin VivoStructure-Activity Relationships of Novel Androgen Receptor Ligands with Multiple Substituents in the B-Ring

20 citations , September 2005 in “Endocrinology”

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

research Mrp3, a Mitogen-Regulated Protein/Proliferin Gene Expressed in Wound Healing and in Hair Follicles

19 citations , May 2001 in “Endocrinology”

Mrp3 may aid in wound healing and hair growth.

Estrogen-Dependent Development of Sex Differences in Somatostatin Neurons of the Hypothalamic Periventricular Nucleus

research Estrogen-Dependent Ontogeny of Sex Differences in Somatostatin Neurons of the Hypothalamic Periventricular Nucleus*

19 citations , March 1998 in “Endocrinology”

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

research Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque

19 citations , January 1997 in “Endocrinology”

Testosterone can slow hair growth in adult monkeys, but a blocker called RU 58841 can counteract this and potentially help hair regrow.

research Do Anti-androgens Have Potential as Therapeutics for COVID-19?

18 citations , June 2021 in “Endocrinology”

Anti-androgens might help reduce COVID-19 severity in men.

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