94 citations
,
January 2000 in “The Journal of Clinical Endocrinology and Metabolism” Spironolactone most effective for hirsutism, but has side effects.
93 citations
,
June 2001 in “The Journal of Clinical Endocrinology and Metabolism” Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.
61 citations
,
June 2016 in “Clinical Medicine” PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.
33 citations
,
October 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride reduces hair growth and is safe for women with excessive hair.
24 citations
,
October 1995 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The nafarelin test can reliably distinguish between gonadotropin deficiency and delayed puberty in teenage boys.
16 citations
,
April 2012 in “Gynecological Endocrinology” Older obese women with PCOS have higher cardiovascular and metabolic risks despite lower androgen levels.
15 citations
,
June 1995 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride doesn't affect erections much, but may decrease libido in men.
11 citations
,
January 2013 in “Indian Journal of Endocrinology and Metabolism” A woman with a rare adrenal tumor and hormonal disorder had improved testosterone levels after surgery, but her menstrual irregularities continued.
10 citations
,
June 2010 in “Fertility and Sterility” Patients with PCOS tend to score their hirsutism higher than clinicians, making self-scoring less useful for diagnosis.
10 citations
,
January 2003 in “Seminars in reproductive medicine” The article explains how to identify and treat excessive hair growth in women, which can be distressing and may signal other health problems.
6 citations
,
August 1996 in “The Journal of Clinical Endocrinology and Metabolism” MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
4 citations
,
November 2012 in “Obstetrics, Gynaecology & Reproductive Medicine” Lifestyle changes and clomiphene are first-line treatments for infertility in women with PCOS, with other options available if these fail.
2 citations
,
January 2017 in “Cambridge University Press eBooks” Manage PCOS in primary care with weight loss, psychological support, medication, and monitoring for health risks.
1 citations
,
December 2015 in “Endocrinology” Decanoic acid may help treat PCOS by reducing androgen levels and improving glucose sensitivity.
1 citations
,
August 2013 in “Springer eBooks” Birth control pills and anti-androgen medications help manage hair growth, acne, and hair loss in women with PCOS.
February 2026 in “World Journal of Interdisciplinary Innovation Sciences” Cinnamon may help improve insulin sensitivity in women with PCOS.
June 2025 in “International Journal of Environmental Sciences” CLEC10A and interleukin-42 can help identify PCOS patients' response to Metformin treatment.
February 2024 in “Brazilian Journal of Implantology and Health Sciences” PCOS often causes skin issues like excess hair, acne, and hair loss, needing early treatment.
June 2023 in “Journal of multidisciplinary sciences (Online)” PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.
February 2022 in “Journal of Armed Forces Medical College” The patient with autoimmune hypothyroidism improved after treatment for thyroid and associated conditions.
February 2021 in “International Journal of Science and Research (IJSR)” A higher testosterone/dihydrotestosterone ratio in PCOS patients may indicate worse metabolic health.
May 2019 in “Paediatrics and child health” The document concludes that personalized treatment, including lifestyle changes and medication, is essential for managing PCOS in teenagers, while also addressing their psychological well-being.
November 2004 in “John Wiley & Sons, Ltd eBooks” Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.
7 citations
,
January 2016 in “Experimental and Clinical Endocrinology & Diabetes” Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.
2 citations
,
January 2023 in “Research Square (Research Square)” Managing emotional distress, obesity, insulin resistance, and high male hormones is crucial for improving well-being in women with PCOS.
November 2025 in “Frontiers in Endocrinology” Apigenin and ellagic acid may help manage PCOS symptoms.
October 2023 in “Frontiers in endocrinology” Effective PCOS treatments require targeting specific signaling pathways.
August 2024 in “Journal of Contemporary Medical Practice” Professor Ma Shuanquan treats hair loss by using Chinese medicine to improve liver, spleen, and kidney health.
66 citations
,
September 2008 in “Dermatologic therapy” The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.
50 citations
,
March 2011 in “European Journal of Endocrinology” Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.