24 citations
,
November 2019 in “Experimental Dermatology” PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
November 2022 in “Journal of Investigative Dermatology” Blocking mTORC1 activity could increase hair pigmentation and potentially reverse greying.
January 2018 in “Hair transplant forum international” Nutrafol might help reduce hair loss due to inflammation, but more evidence is needed.
January 2014 in “theses.fr (ABES)” Androgens regulate Sertoli cells and affect fertility through specific receptors and coregulators.
50 citations
,
June 2014 in “Experimental and Clinical Endocrinology & Diabetes” Hair hormone levels can indicate obesity-related changes and are useful for research and clinical practice.
21 citations
,
May 2001 in “PubMed” Androgen hormones affect hair growth and oil production, influencing conditions like hair loss and acne.
October 2022 in “Frontiers in Cell and Developmental Biology” Aging skin is affected by inflammation, reduced stem cell function, and slower wound healing.
March 2021 in “Der Hautarzt” Neuroendocrine paraneoplastic syndromes often show skin changes, helping early diagnosis and requiring a team approach for best care.
23 citations
,
November 2007 in “Actas Dermo-Sifiliográficas” Thyroid hormone (T3) may reverse gray hair by stimulating hair growth.
7 citations
,
April 2011 in “American journal of obstetrics and gynecology” A woman's virilization symptoms were caused by her partner's use of testosterone cream, which resolved after they separated.
May 2023 in “Frontiers in Endocrinology” Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.
658 citations
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June 2003 in “Endocrine reviews” Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
1 citations
,
October 2025 in “EBioMedicine” Women have a higher DHT/testosterone ratio than men, possibly due to gut bacteria activity.
January 2022 in “IntechOpen eBooks” Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.
50 citations
,
February 2013 in “Annals of Clinical Biochemistry” Understanding how DHT works is important for diagnosing and treating hormone-related disorders.
16 citations
,
June 2022 in “Journal of Pediatric Endocrinology and Metabolism” Reducing phthalate exposure may help prevent early puberty in girls.
12 citations
,
July 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” Men with hormonal imbalances similar to PCOS may have increased risk of metabolic and heart diseases.
5 citations
,
January 2017 in “Acta Endocrinologica” High androgen levels in postmenopausal women may suggest an ovarian tumor, and removing it can improve heart and metabolic health.
November 2025 in “European Journal of Endocrinology” Hair steroid profiling is a feasible, non-invasive alternative to serum analysis for assessing hormone levels and metabolism.
May 2023 in “Research and Practical Medicine Journal” Severe COVID-19 may increase lung cancer risk and affect treatment in women due to hormonal changes.
September 2021 in “Research Square (Research Square)” Certain hormone levels can help diagnose P450 oxidoreductase deficiency.
18 citations
,
October 2017 in “PLOS ONE” The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.
9 citations
,
December 2021 in “Androgens” Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.
2 citations
,
January 2023 in “Pharmaceuticals” Sex and sex hormones can affect brain inflammation in Parkinson's disease, with male mice being more affected and female mice showing a protective effect.
168 citations
,
January 2005 in “Journal of Investigative Dermatology” Male and female mice have different skin thickness, and hormones affect their skin and hair growth differently.
139 citations
,
December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
110 citations
,
January 1984 in “Progress in brain research” Gonadal hormones may influence sex differences in play fighting in animals, but their effect on human spatial behavior is unclear and needs more research.
100 citations
,
September 2017 in “Molecular and Cellular Endocrinology” Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
67 citations
,
December 2013 in “Journal of Biological Chemistry” SCD1 is crucial for skin health and overall energy balance.
61 citations
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April 2018 in “Frontiers in endocrinology” Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.