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A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Finasteride blocks progesterone's effect on absence seizures in rats.

Flavonoids and Nod factors are key for legume plant growth and could help in sustainable farming.

Liquorice has medicinal benefits, including antioxidant, anti-inflammatory, antimicrobial, antiulcer, and antiviral effects.

The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Topical spironolactone cream doesn't cause hormone-related side effects in the body.

Piperonylic acid speeds up wound healing by reducing inflammation and boosting collagen.

Aspergillus niger culture creates two finasteride derivatives with enzyme-inhibiting effects.

A Rathke's cleft cyst caused hormonal imbalances and symptoms in a 68-year-old woman.

The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.

Skin may help in getting rid of excess iron through the process of skin cell renewal.

The research found different metabolism changes in PCOS patients and suggested new potential markers for diagnosing PCOS with or without insulin resistance.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

Spironolactone treatment increases the amount of testosterone available in the body.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Neurosteroids show promise for treating epilepsy and more research is needed.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.

A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.

Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.

Testosterone is crucial for development, growth, and various body functions in mammals.

Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.