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Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

The FDA rejected a testosterone drug again due to safety concerns.

Bicalutamide does not significantly affect liver enzymes and is a safe anti-androgen option for transfeminine individuals.

Aromatase inhibitors can cause skin issues, especially with anastrozole and exemestane, so monitoring is important.

New progesterone-based compounds can block male hormones.

New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.

Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.

A combination of desogestrel and ethinyl oestradiol effectively reduces hair growth in hirsute women.

Anabolic steroids and SARMs can cause serious liver damage.

Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Men with early-onset hair loss are less responsive to bromocriptine's heart and metabolism benefits.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

New treatments for male hypogonadism are easier to use and target specific tissues to reduce side effects.

LX-38 is a safer drug option for treating prostate issues and hair loss without hormonal side effects.

17α-estradiol extends lifespan and improves metabolism in male mice through the estrogen receptor α.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

The drug showed promise in treating renal cell carcinoma with manageable side effects.

LX-38 is a safer drug option for hair loss and prostate issues without hormonal side effects.

Abemaciclib can cause skin, hair, and nail problems, leading some patients to stop using it.

5 alpha reductase inhibitors can cause sexual, cognitive, and muscle side effects, and may slightly increase aggressive cancer risk.

PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.