research Protein and amino acid composition of hair from mice carrying the naked (N) gene
The N gene affects the protein makeup of mouse hair.
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research Hair diseases: a big problem on a small surface
Many hair diseases, including those caused by medications and psychological issues, can lead to hair loss and require proper treatment and specialist care.
research Cosmetic Dermatology
Common cosmetic dermatology techniques improve skin damaged by the sun and aging.
research High-resolution mass spectrometric investigation of the phase I and II metabolites of finasteride in pig plasma, urine and bile
Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.
research Structure-guided PEGylated fibroblast growth factor 2 variants accelerate wound healing with improved stability
Compound 6 is a promising candidate for better wound healing.
research Homeodynamic Rejuvenation: an adaptive framework for resetting skin aging
Homeodynamic Rejuvenation aims to improve skin's stress management and recovery to combat aging.
research Evaluating the hormonal and biochemical markers in womens with polycystic ovarian syndrome PCOS in Missan Province
Women with PCOS in Missan Province have higher weight, hormonal imbalances, and metabolic issues.
research Age-related downregulation of dihydrotestosterone-inactivating enzymes in human scalp sebaceous glands
AKR1C enzymes in scalp glands decrease with age, possibly affecting hair loss.
research Sebocytes are the Key Regulators of Androgen Homeostasis in Human Skin
Sebocytes play a key role in controlling androgen levels in human skin.
research Hair Follicle Regeneration Using Grafted Rodent and Human Cells
Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
research Steroid Biomarkers and Genetic Studies Reveal Inactivating Mutations in Hexose-6-Phosphate Dehydrogenase in Patients with Cortisone Reductase Deficiency
Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
research Recent Advances in the Structural Design of Photosensitive Agent Formulations Using “Soft” Colloidal Nanocarriers
New nanocarriers improve drug delivery for disease treatment.
research Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice
Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.
research SARS-CoV-2 Non-Structural Proteins and Their Roles in Host Immune Evasion
SARS-CoV-2 proteins help the virus avoid the immune system, delaying response and increasing inflammation.
research The neurosteroidogenic enzyme 5α-reductase modulates the role of D1 dopamine receptors in rat sensorimotor gating
5α-reductase affects dopamine receptors linked to sensorimotor gating, which may help understand disorders like schizophrenia.
research Immunohistochemical Evaluation of Androgen Receptor and Nerve Structure Density in Human Prepuce from Patients with Persistent Sexual Side Effects after Finasteride Use for Androgenetic Alopecia
Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.
research Repurposing existing drugs for COVID-19: an endocrinology perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research The CD44+ALDH+ Population of Human Keratinocytes Is Enriched for Epidermal Stem Cells with Long-Term Repopulating Ability
Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
research Detection of urine metabolites in polycystic ovary syndrome by UPLC triple-TOF-MS
Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.
research Androgen receptor: A promising therapeutic target in breast cancer
The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
research Synthesis and biological evaluation of novel unsaturated carboxysteroids as human 5α-reductase inhibitors: A legitimate approach
New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.
research iRhom2 Mutation Leads to Aberrant Hair Follicle Differentiation in Mice
A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.
research Two years of SARS-CoV-2 infection (2019–2021): structural biology, vaccination, and current global situation
Continued vaccine and drug development is crucial due to new virus variants and regional infection spikes.
research Root hair growth from the pH point of view
pH changes are crucial for root hair growth because they affect enzymes and proteins that control the cell wall and growth.
research A comparative in vivo and in vitro evaluation of hair growth potential of extracts and an isolate from petroleum ether extract of Cuscuta reflexa Roxb
Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.
research Bioarchitectural Design of Bioactive Biopolymers: Structure–Function Paradigm for Diabetic Wound Healing
Bioactive biopolymers can improve diabetic wound healing by enhancing tissue regeneration.
research PNKP is required for maintaining the integrity of progenitor cell populations in adult mice
PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.
research Association of ACE2, Insulin Resistance, and Other Parameters in Obese Polycystic Ovary Syndrome Patients Infected with COVID-19
PCOS women with COVID-19 have higher cardiometabolic risks.
research The potential of androgenic alopecia management from plant derivatives
Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.
research Reversing Time with Peptides: Mechanisms, Classifications, and Innovations in Anti-aging Interventions
Anti-aging peptides can improve skin appearance but need better delivery methods and more research.