110 citations
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February 2024 in “Journal of Chemical Information and Modeling” PandaOmics uses AI to find new disease treatment targets and biomarkers.
87 citations
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February 2000 in “Journal of Investigative Dermatology” Stem cells in developing hair follicles move to specific areas as they mature.
82 citations
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March 2013 in “PLoS ONE” Vemurafenib causes skin side effects similar to RASopathies, requiring regular skin checks and UVA protection.
80 citations
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January 1979 in “Journal of Surgical Oncology” Keratoacanthoma is a common, usually non-dangerous skin tumor that looks like squamous cell carcinoma but rarely becomes severe.
73 citations
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November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Markers help differentiate between apocrine and eccrine sweat glands to identify sweat gland tumors.
71 citations
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October 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” Vitamin D receptor helps prevent skin cancer and supports skin health.
57 citations
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January 2020 in “International Journal of Molecular Sciences” PADs are crucial for healthy skin and hair, and their imbalance can cause skin and hair disorders.
56 citations
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July 2004 in “Mechanisms of Development” Pax9 is crucial for proper tongue surface development and preventing skin-like changes.
54 citations
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September 1999 in “PubMed” K15 staining helps distinguish basal cell carcinoma from trichoepithelioma.
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October 2003 in “Developmental Biology” Too much Sonic Hedgehog protein stops hair growth in embryos.
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March 2010 in “PloS one” C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.
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January 2024 in “iScience” Stress keratins are expressed less in diseased skin and are linked to differentiation, inflammation, and immunity.
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August 2024 in “Current Issues in Molecular Biology” Keratins 6, 16, and 17 increase in damaged or diseased skin and may help diagnose skin issues.
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October 2007 in “Journal of Investigative Dermatology” Betacellulin helps blood vessel growth in wounds but delays hair growth.
26 citations
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June 2024 in “Frontiers in Immunology” SOCS1 and SOCS3 help control skin inflammation and are important for developing treatments for skin diseases.
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March 2016 in “Journal of Investigative Dermatology” TIP39 and PTH2R help control calcium levels and skin cell development.
22 citations
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April 2017 in “Journal of Investigative Dermatology” Non-coding RNAs are crucial for skin development and health.
22 citations
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December 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” A mouse gene mutation increases the risk of skin cancer.
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January 2019 in “Aging” Lack of functional CYLD in mice leads to early aging and cancer.
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July 2008 in “BMC Genomics” Alpha 6 + /MHCI - cells have stem cell traits and are similar to mouse hair follicle stem cells.
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March 2021 in “EMBO Reports” PRSS35 enzyme may help start skin tumors and could be a target for cancer treatment.
8 citations
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July 2015 in “European journal of histochemistry” Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.
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August 2022 in “Experimental dermatology” Blocking YAP/TAZ could be a new way to treat skin cancer.
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December 2023 in “Journal of Clinical Medicine” Abnormal growth factor metabolism may link psoriasis and metabolic syndrome, and obesity can affect psoriasis treatment effectiveness.
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April 2022 in “Frontiers in Medicine” Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
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September 2018 in “Journal of Investigative Dermatology” Keratinocyte cytokines and genetic variations influence the development of moles and skin pigmentation.
4 citations
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April 2024 in “The Journal of Cell Biology” Caspase-1 helps hair stem cells move to heal wounded or inflamed skin.
4 citations
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January 2019 in “Journal of cutaneous pathology” The mTOR pathway may be involved in the development of hair follicle tumors, with higher activity in malignant tumors.
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March 2013 in “InTech eBooks” Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
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December 2003 in “Archives of Pathology & Laboratory Medicine” The nodule was a benign cutaneous lymphadenoma, not cancer, and was successfully removed.