338 citations
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July 2009 in “Development” Sox2-positive cells determine specific hair follicle types in mammals.
25 citations
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November 2020 in “Proceedings of the National Academy of Sciences” HoxC genes are crucial for normal hair and nail development.
January 2018 in “Stem cell biology and regenerative medicine” ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.
99 citations
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September 2004 in “Development” Proper hedgehog signaling is crucial for maintaining healthy skin stem cells.
98 citations
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December 2015 in “The Journal of Cell Biology” Keratin is crucial for skin barrier formation and affects mitochondrial function.
90 citations
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February 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Interleukin-1 increases keratin K6 production in skin cells.
73 citations
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January 2016 in “International review of cell and molecular biology” Cornification evolved from keratinization in vertebrates, with differences between mammals and sauropsids.
43 citations
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January 2016 in “Cellular physiology and biochemistry” Epidermal Growth Factor helps hair follicle cells grow and move by activating a specific cell signaling pathway.
39 citations
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January 2015 in “International journal for parasitology/International Journal for Parasitology” Epidermal keratinocytes start wound healing and inflammation after schistosome infection.
29 citations
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April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
25 citations
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December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
22 citations
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August 2006 in “Critical Reviews in Plant Sciences” The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.
18 citations
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January 2013 in “Journal of Investigative Dermatology” WIF1 helps keep skin stem cells inactive to prevent excessive cell growth.
10 citations
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August 2013 in “Experimental Dermatology” Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.
8 citations
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January 2019 in “Experimental Dermatology” The 3D skin model is better for hair growth research and testing treatments.
7 citations
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January 2020 in “Frontiers in Pharmacology” Jagged1 and Epidermal Growth Factor together significantly increased hair growth in mice with androgen-suppressed hair.
7 citations
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July 2016 in “Journal of Biomedical Materials Research Part A” cGEL hydrogel improves melanin production in skin cells, making it a promising option for skin treatments.
5 citations
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September 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” Basal stem cells in the skin have distinct types that are crucial for skin structure and health.
3 citations
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November 2021 in “Frontiers in Genetics” Certain genes are linked to the quality of cashmere in goats.
3 citations
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September 2021 in “Journal of Clinical Medicine” Epidermal signaling helps regenerate fingertip tissue.
2 citations
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July 2015 in “Archives of Dermatological Research” A new gene variant in the DSP gene is linked to a unique type of hair loss.
1 citations
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August 2013 in “The Journal of Cell Biology” Lack of Evi in skin causes psoriasis-like symptoms in mice.
Lysine carboxymethyl cysteinate (LCC) protects skin from UVB damage by activating autophagy.
April 2026 in “Development” Hemidesmosomes and Notch signaling help skin cells mature by moving them to the outer layer.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
January 2021 in “Acta Scientiae Veterinariae” Levothyroxine effectively treated a dog's skin and hair problems caused by hypothyroidism.
Skin stem cells in hair follicles are important for touch sensation.
42 citations
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May 1997 in “The Journal of Biochemistry” PAD type III enzyme is specific to rat skin and hair follicles.
14 citations
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January 2008 in “Dermatology” Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.
9 citations
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July 2007 in “Journal of Investigative Dermatology” Claudin expression changes help the skin respond to injury.