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Pharmacological Activation of Thermo-Transient Receptor Potential Vanilloid 3 Channels Inhibits Hair Growth by Inducing Cell Death of Hair Follicle Outer Root Sheath

research Pharmacological Activation of Thermo–Transient Receptor Potential Vanilloid 3 Channels Inhibits Hair Growth by Inducing Cell Death of Hair Follicle Outer Root Sheath

12 citations , June 2019 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics”

Activating TRPV3 channels stops hair growth by killing hair follicle cells.

research Activation of Transient Receptor Potential Vanilloid-3 Inhibits Human Hair Growth

105 citations , May 2011 in “The journal of investigative dermatology/Journal of investigative dermatology”

Activating TRPV3 stops human hair growth.

Vascular Endothelial Growth Factor Protects CD200-Rich and CD34-Positive Hair Follicle Stem Cells Against Androgen-Induced Apoptosis Through the Phosphoinositide 3-Kinase/Akt Pathway in Patients With Androgenic Alopecia

research Vascular Endothelial Growth Factor Protects CD200-Rich and CD34-Positive Hair Follicle Stem Cells Against Androgen-Induced Apoptosis Through the Phosphoinositide 3-Kinase/Akt Pathway in Patients With Androgenic Alopecia

11 citations , September 2019 in “Dermatologic Surgery”

A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.

research Growth factor mimetics for skin regeneration: In vitro profiling of primary human fibroblasts and keratinocytes

3 citations , May 2021 in “Archiv der Pharmazie”

SUN11602 and ONO-1301 could help in skin healing and creating artificial skin.

research Strawberry guava extract promotes hair growth by enhancing skin blood flow and vascular endothelial growth factor production

July 2026 in “Functional Foods in Health and Disease”

Strawberry guava extract helps hair grow by improving blood flow and certain growth factors.

research WNT Signaling in the Control of Hair Growth and Structure

271 citations , March 1999 in “Developmental biology”

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

Platelet-Derived Growth Factor Regulates the Proliferation and Differentiation of Human Melanocytes in a Differentiation-Stage-Specific Manner

research Platelet-derived growth factor regulates the proliferation and differentiation of human melanocytes in a differentiation-stage-specific manner

10 citations , May 2016 in “Journal of Dermatological Science”

PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.

Evaluation of Non-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems

research Evaluation of Not-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems

136 citations , February 2017 in “International Journal of Molecular Sciences”

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

research The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling

134 citations , January 2011 in “Development”

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

research Hair growth effects of Laminaria japonica extract and growth factor mixture on a C57BL/6 mouse model

3 citations , January 2016 in “Biotechnology and Bioprocess Engineering”

Laminaria japonica extract with IGF-1 improved mouse hair growth and could be a potential alopecia treatment.

Cell Wall-Associated Root Hair Specific 10, a Proline-Rich Receptor-Like Kinase, Is a Negative Modulator of Arabidopsis Root Hair Growth

research Cell wall-associated ROOT HAIR SPECIFIC 10, a proline-rich receptor-like kinase, is a negative modulator of Arabidopsis root hair growth

33 citations , February 2016 in “Journal of Experimental Botany”

ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.

research RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling

21 citations , February 2017 in “PLoS ONE”

RhoA helps skin stem cells grow, aiding wound healing.

17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells

research 17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells

18 citations , March 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

research BMP-FGF Signaling Axis Mediates Wnt-Induced Epidermal Stratification in Developing Mammalian Skin

84 citations , October 2014 in “PLoS Genetics”

Wnt signaling is essential for forming the skin's spinous layer through a BMP-FGF pathway.

research Development of growth factor-incorporating liposomes for integration into scaffolds as a method to improve tissue regeneration

12 citations , September 2021 in “The International Journal of Developmental Biology”

Liposomal carriers can improve tissue regeneration by stabilizing and retaining growth factors.

research Inhibition of Insulin-Like Growth Factor-1–Induced Sebum Production by Bilobetin in Cultured Human Sebocytes

8 citations , January 2019 in “Annals of Dermatology”

Bilobetin may help reduce acne by decreasing sebum production.

In Vitro Expansion of Human Mesenchymal Stem Cells and Hepatocytes Using Purified Platelet-Derived Growth Factors: A Potential Therapeutic Modality for Liver Fibrosis

research In vitro expansion of human mesenchymal stem cells and hepatocytes using purified platelet derived growth factors, a potential therapeutic modality for liver fibrosis

April 2023 in “Egyptian journal of Immunology”

10% hPL is best for growing mesenchymal stem cells, while 10% FBS is best for hepatocytes.

research Drought-induced SlCLE10 coordinates ethylene biosynthesis and root hair development to confer osmotic stress tolerance in tomato

January 2026 in “Plant Communications”

Overexpressing SlCLE10 in tomatoes boosts root hair growth and drought tolerance.

research AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis

December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

Plasma Rich in Growth Factors for the Treatment of Androgenetic Alopecia

research Plasma rich in growth factors (PRGF) for the treatment of androgenetic alopecia

7 citations , June 2015 in “European Journal of Plastic Surgery”

PRGF treatment safely and effectively helps hair loss.

research Dickkopf-related Protein 2 Promotes Hair Growth by Upregulating the Wnt/β-catenin Signaling Pathway in Human Dermal Papilla Cells

6 citations , January 2024 in “Annals of Dermatology”

Dickkopf-related Protein 2 can help hair grow by activating a specific cell pathway.

research Dermal-epidermal interactions—follicle-derived cell populations in the study of hair-growth mechanisms

19 citations , July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology”

Dermal-epidermal interactions are crucial for hair growth and maintenance.

GC-MS Profiling and In Silico Prediction of MAPK Receptor Activation by Fatty Acids of Watercress Oil for Hair Growth Marketed in Saudi Arabia

research GC–MS profiling and in silico prediction of MAPK receptor activation by fatty acids of watercress oil for hair growth marketed in Saudi Arabia

5 citations , January 2021 in “Journal of Saudi Chemical Society”

Watercress oil may promote hair growth by activating specific receptors.

Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways

research Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways

14 citations , June 2018 in “Frontiers in pharmacology”

Green tea compound EGCG helps mink hair follicles grow by affecting certain cell growth pathways.

Plasma Rich in Growth Factors as an Adjuvant Treatment for the Management of Frontal Fibrosing Alopecia: A Retrospective Observational Clinical Study

research Plasma Rich in Growth Factors as an Adjuvant Treatment for the Management of Frontal Fibrosing Alopecia: A Retrospective Observational Clinical Study

11 citations , May 2023 in “Journal of Cutaneous Medicine and Surgery”

Plasma Rich in Growth Factors may help reduce hair loss in Frontal Fibrosing Alopecia.

Human Platelet Lysate Versus Minoxidil Stimulates Hair Growth by Activating Anagen Promoting Signaling Pathways

research Kaempferol enhances hair growth by regulating JAK3/STAT6 and TGF-β/Smad signaling in human dermal papilla cells and a C57BL/6 mousemodel

October 2025 in “Records of Natural Products”

Kaempferol promotes hair growth and could be a natural treatment for hair loss.

research The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function

3 citations , May 2022 in “Oncogene”

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

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