research Targeting the Wnt pathways for therapies
Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
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research Dermal white adipose tissue: a new component of the thermogenic response
Skin fat helps with body temperature control and has other active roles in health.
research TGF-β Family Signaling in Epithelial Differentiation and Epithelial–Mesenchymal Transition
The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
research Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells
Muscles and nerves that cause goosebumps also help control hair growth.
research Stem cells and the circadian clock
The circadian clock influences the behavior and regeneration of stem cells in the body.
research Aberrant Activation of the Hedgehog Signaling Pathway in Malignant Hematological Neoplasms
Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
research Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk
Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.
research FOXN1 Deficiency: from the Discovery to Novel Therapeutic Approaches
New treatments for immune disorders caused by FOXN1 deficiency are promising.
research The Dynamic Duo: Niche/Stem Cell Interdependency
Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.
research The Role of Immature and Mature Adipocytes in Hair Cycling
Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.
research Tissue engineering strategies for human hair follicle regeneration: How far from a hairy goal?
Fully regenerating human hair follicles not yet achieved.
research Role of β-Catenin Activation Levels and Fluctuations in Controlling Cell Fate
Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
research Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration
Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.
research Interfacial Adipose Tissue in Systemic Sclerosis
Unique fat cells near fibrotic areas contribute to systemic sclerosis progression.
research A guide to studying human dermal adipocytes in situ
The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
research Expansion and characterization of epithelial stem cells with potential for cyclical hair regeneration
A specific group of stem cells can help regenerate hair continuously.
research Mouse Spermatogenesis Reflects the Unity and Diversity of Tissue Stem Cell Niche Systems
Mouse spermatogenesis shows that stem cells can behave flexibly and move widely in open environments.
research A Unique Expression of Keratin 14 in a Subset of Trophoblast Cells
Keratin 14 is uniquely found in a specific group of placental cells.
research Capturing Stem Cell Behavior Using Intravital and Live Cell Microscopy
Stem cells are more dynamic and adaptable than previously believed.
research Revisiting the significance of keratin expression in complex epithelia
Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.
research Mesenchymal stem cell‐derived exosomes for organ development and cell‐free therapy
MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
research Rapid mechanosensitive migration and dispersal of newly divided mesenchymal cells aid their recruitment into dermal condensates
Newly divided skin cells quickly move to join skin structures due to tissue tension and specific signals.
research ESGCT and FSGT Collaborative Congress Helsinki, Finland September 17–20, 2015 Abstracts
The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
research γδ17 T cell-stromal networks modulate matrix composition and vascularity in foreign body response
γδ T cells help control tissue scarring and blood vessel growth in response to foreign objects.
research Multi-scale spatial mapping of cell populations across anatomical sites in healthy human skin and basal cell carcinoma
The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
research Revisiting the significance of keratin expression in complex epithelia
Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.
research BIPHENOTYPIC LEUKAEMIA
Acute leukemias with the Philadelphia chromosome may be biphenotypic, and identifying this is important for proper treatment.
research Herbal Approaches for the Management of Premature Hair Greying: Mechanisms, Phytoconstituents and Delivery Strategies
Herbal remedies show promise for managing premature hair greying but need more research.
research Dissecting the boundary of quiescence and activation of murine melanocyte stem cells in the hair follicle niche
Melanocyte stem cells in hair follicles are key to understanding and potentially preventing hair graying.
research Adipose-derived stem cell exosomes promote critical-sized bone defect repair by enhancing the homing of bone marrow mesenchymal stem cells
Exosomes from fat-derived stem cells help repair large bone defects by attracting and enhancing bone marrow stem cells.